Art

J-GLOBAL ID：201902233037889988   Reference number：19A1759987

Rutin inhibits carfilzomib-induced oxidative stress and inflammation via the NOS-mediated NF-κB signaling pathway

ルチンはNOS仲介NF-κBシグナル伝達経路を介してカルフィルzomib誘導酸化ストレスと炎症を阻害する【JST・京大機械翻訳】

Author (9)： Al-Harbi Naif O. (Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, Kingdom of Saudi Arabia) ,  Imam Faisal (Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, Kingdom of Saudi Arabia) ,  Al-Harbi Mohammed M. (Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, Kingdom of Saudi Arabia) ,  Al-Shabanah Othman A. (Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, Kingdom of Saudi Arabia) ,  Alotaibi Moureq Rashed (Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, Kingdom of Saudi Arabia) ,  As Sobeai Homood M. (Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, Kingdom of Saudi Arabia) ,  Afzal Muhammad (Department of Pharmacology and Toxicology, College of Pharmacy, Al Jauf University, Sakakah, Kingdom of Saudi Arabia) ,  Kazmi Imran (Department of Pharmacology and Toxicology, School of Pharmacy, Glocal University, Saharan Pur, India) ,  Al Rikabi Ammar Cherkess (Department of Pathology, College of Medicine, King Khalid University Hospital, Riyadh, Kingdom of Saudi Arabia)
Material： Inflammopharmacology
Volume： 27  Issue： 4  Page： 817-827  Publication year： 2019 
JST Material Number： W0656A  ISSN： 0925-4692  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Abstract/Point： Carfilzomib (CFZ), a proteasom...

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Thesaurus term： enzyme ,  *oxidative stress ,  Rattus ,  renal toxicity ,  flavonoid ,  administration (biology) ,  leucocyte ,  *Inflammation ,  protective action ,  *NF-kappaB ,  Caspase 3 ,  antioxidant enzyme ,  Myomorpha ,  oxygen heterocyclic compound ,  glycoside (except carbohydrate) ,  polyphenol ,  disaccharide ,  pyranoside ,  polynuclear aromatic compound ,  hydroxy ketone
Semi thesaurus term： 組織病理 , 【Automatic Indexing@JST】

Author keywords (6)： Rutin ,  Carfilzomib ,  Nephrotoxicity ,  NOS-2 ,  NF-κB ,  Histopathology

JST classification (2)： Immunological reaction in general  (ED03010T) ,  Basic research of pharmacology of crude drugs  (GX06020J)

Substance index (2)： Olmesartan ,  Rutin

Terms in the title (7)： ルチン ,  仲介 ,  NF-κB ,  シグナル伝達経路 ,  ストレス ,  炎症 ,  阻害