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J-GLOBAL ID：201902233753760500   Reference number：19A0963674

Deletion of Bmal1 Prevents Diet-Induced Ectopic Fat Accumulation by Controlling Oxidative Capacity in the Skeletal Muscle

BMAL1の欠失は骨格筋における酸化能を制御することにより食餌誘発異所性脂肪蓄積を予防する【JST・京大機械翻訳】

Author (10)： Wada Taira (Laboratory of Health Science, School of Pharmacy, Nihon University, 7-7-1 Narashinodai, Chiba, Funabshi 274-8555, Japan) ,  Ichihashi Yuya (Laboratory of Health Science, School of Pharmacy, Nihon University, 7-7-1 Narashinodai, Chiba, Funabshi 274-8555, Japan) ,  Suzuki Emi (Laboratory of Health Science, School of Pharmacy, Nihon University, 7-7-1 Narashinodai, Chiba, Funabshi 274-8555, Japan) ,  Kosuge Yasuhiro (Laboratory of Pharmacology, School of Pharmacy, Nihon University, 7-7-1 Narashinodai, Chiba, Funabshi 274-8555, Japan) ,  Ishige Kumiko (Laboratory of Pharmacology, School of Pharmacy, Nihon University, 7-7-1 Narashinodai, Chiba, Funabshi 274-8555, Japan) ,  Uchiyama Taketo (Laboratory of Organic Chemistry, School of Pharmacy, Nihon University, 7-7-1 Narashinodai, Chiba, Funabshi 274-8555, Japan) ,  Makishima Makoto (Division of Biochemistry, Department of Biomedical Sciences, School of Medicine, Nihon University, 30-1 Oyaguchi-Kamicho, Itabashi-ku, Tokyo 173-8610, Japan) ,  Nakao Reiko (Biological Clock Research Group, Biomedical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Ibaraki 305-8566, Japan) ,  Oishi Katsutaka (Biological Clock Research Group, Biomedical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Ibaraki 305-8566, Japan) ,  Shimba Shigeki (Laboratory of Health Science, School of Pharmacy, Nihon University, 7-7-1 Narashinodai, Chiba, Funabshi 274-8555, Japan)
Material： International Journal of Molecular Sciences (Web)  (Int J Mol Sci (Web))
Volume： 19  Issue： 9  Page： 2813  Publication year： 2018 
JST Material Number： U7038A  ISSN： 1422-0067  CODEN： IJMCFK  Document type： Article
Article type： 原著論文  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Brain and muscle arnt-like pro...

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Thesaurus term： *skeletal muscle ,  Overnutrition ,  phosphorylation ,  actin ,  transcription factor ,  *oxidation ,  Energy Metabolism ,  Mus musculus ,  C-C ligase ,  energy consumption ,  Calcium ,  characterization ,  diurnal rhythm ,  Running ,  *BMAL1 ,  Myomorpha

Author keywords (4)： skeletal muscle ,  circadian rhythm ,  ectopic fat ,  BMAL1

JST classification (2)： Cell physiology in general  (EF02010S) ,  Basic medicine on musculoskeletal system  (GG01020B)

Reference (44)：

• Ikeda, M.; Nomura, M. cDNA cloning and tissue-specific expression of a novel basic helix-loop-helix/PAS protein (BMAL1) and identification of alternatively spliced variants with alternative translation initiation site usage. Biochem. Biophys. Res. Commun. 1997, 233, 258-264.
• Hogenesch, J.B.; Gu, Y.Z.; Jain, S.; Bradfield, C.A. The basic-helix-loop-helix-PAS orphan MOP3 forms transcriptionally active complexes with circadian and hypoxia factors. Proc. Natl. Acad. Sci. USA 1988, 95, 5474-5479.
• Takahata, S.; Sogawa, K.; Kobayashi, A.; Ema, M.; Mimura, J.; Ozaki, N.; Fujii-Kuriyama, Y. Transcriptionally active heterodimer formation of an Arnt-like PAS protein, Arnt3, with HIF-1a, HLF and clock. Biochem. Biophys. Res. Commun. 1998, 248, 789-794.
• Gekakis, N.; Staknis, D.; Nguyen, H.B.; Davis, F.C.; Wilsbacher, L.D.; King, D.P.; Takahashi, J.S.; Weitz, C.J. Role of the clock protein in the mammalian circadian mechanism. Science 1988, 280, 1564-1569.
• Yoo, S.H.; Ko, C.H.; Lowrey, P.L.; Buhr, E.D.; Song, E.J.; Chang, S.; Yoo, O.J.; Yamazaki, S.; Lee, C.; Takahashi, J.S. A noncanonical E-box enhancer drives mouse period2 circadian oscillations in vivo. Proc. Natl. Acad. Sci. USA 2005, 102, 2608-2613.

Terms in the title (9)： BMAL1 ,  欠失 ,  骨格筋 ,  酸化能 ,  食餌 ,  誘発 ,  異所性脂肪 ,  蓄積 ,  予防