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J-GLOBAL ID：201902234086658036   Reference number：19A0143736

Promoting Axon Regeneration in Adult CNS by Targeting Liver Kinase B1

肝臓キナーゼB1標的化による成体CNSにおける軸索再生の促進【JST・京大機械翻訳】

Author (19)： Ohtake Yosuke (Shriners Hospitals Pediatric Research Center, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA) ,  Ohtake Yosuke (Department of Anatomy and Cell Biology, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA) ,  Sami Armin (Shriners Hospitals Pediatric Research Center, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA) ,  Sami Armin (Department of Anatomy and Cell Biology, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA) ,  Jiang Xinpei (Shriners Hospitals Pediatric Research Center, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA) ,  Jiang Xinpei (Department of Anatomy and Cell Biology, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA) ,  Horiuchi Makoto (Shriners Hospitals Pediatric Research Center, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA) ,  Horiuchi Makoto (Department of Anatomy and Cell Biology, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA) ,  Slattery Kieran (Shriners Hospitals Pediatric Research Center, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA) ,  Slattery Kieran (Department of Anatomy and Cell Biology, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA) ,  Ma Lena (Shriners Hospitals Pediatric Research Center, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA) ,  Ma Lena (Department of Anatomy and Cell Biology, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA) ,  Smith George M. (Shriners Hospitals Pediatric Research Center, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA) ,  Smith George M. (Department of Neuroscience, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA) ,  Selzer Michael E. (Shriners Hospitals Pediatric Research Center, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA) ,  Selzer Michael E. (Department of Neurology, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA) ,  Muramatsu Shin-ichi (Division of Neurology, Jichi Medical University, Shimotsuke, Tochigi 329-0498, Japan) ,  Li Shuxin (Shriners Hospitals Pediatric Research Center, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA) ,  Li Shuxin (Department of Anatomy and Cell Biology, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA)
Material： Molecular Therapy  (Mol Ther)
Volume： 27  Issue： 1  Page： 102-117  Publication year： 2019 
JST Material Number： W1762A  ISSN： 1525-0016  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Liver kinase B1 (LKB1), a down...

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Thesaurus term： spinal cord injury ,  neuron ,  *adult (development) ,  *axon ,  cortex ,  Up-Regulation ,  Mus musculus ,  Phosphatidylinositol 3-Kinase ,  vector (genetics) ,  effector ,  *targeting ,  Spinal Cord ,  *kinase ,  immune response ,  STK11 protein ,  damage and injury ,  Myomorpha
Semi thesaurus term： immunological reaction ,  LKB1 , 【Automatic Indexing@JST】

Author keywords (10)： LKB1 ,  neuron growth capacity ,  AAV vector ,  spinal cord injury ,  axon regeneration ,  functional recovery ,  AMPK ,  NUAK1 ,  Erk ,  systemic treatment

JST classification (4)： Basic neurology  (GN01020W) ,  Biological function  (EB03040U) ,  Development(=generation)and differentiation  (EJ16020W) ,  Central nervous system  (EJ12030F)

Terms in the title (6)： 肝臓 ,  キナーゼ ,  標的化 ,  成体 ,  軸索再生 ,  促進