Art

J-GLOBAL ID：201902234492348334   Reference number：19A0647830

Genetic deletion of muscle RANK or selective inhibition of RANKL is not as effective as full-length OPG-fc in mitigating muscular dystrophy

筋ジストロフィーの緩和における完全長OPG-Fcとして有効ではないRANKLの筋肉ランクまたは選択的阻害の遺伝的欠失【JST・京大機械翻訳】

Author (13)： Dufresne Sebastien S. (Centre Hospitalier Universitaire de Quebec-Centre de Recherche du Centre Hospitalier de l’Universite Laval (CHUQ-CRCHUL), Universite Laval, Quebec City, Canada) ,  Boulanger-Piette Antoine (Centre Hospitalier Universitaire de Quebec-Centre de Recherche du Centre Hospitalier de l’Universite Laval (CHUQ-CRCHUL), Universite Laval, Quebec City, Canada) ,  Bosse Sabrina (Centre Hospitalier Universitaire de Quebec-Centre de Recherche du Centre Hospitalier de l’Universite Laval (CHUQ-CRCHUL), Universite Laval, Quebec City, Canada) ,  Argaw Anteneh (Centre Hospitalier Universitaire de Quebec-Centre de Recherche du Centre Hospitalier de l’Universite Laval (CHUQ-CRCHUL), Universite Laval, Quebec City, Canada) ,  Hamoudi Dounia (Centre Hospitalier Universitaire de Quebec-Centre de Recherche du Centre Hospitalier de l’Universite Laval (CHUQ-CRCHUL), Universite Laval, Quebec City, Canada) ,  Marcadet Laetitia (Centre Hospitalier Universitaire de Quebec-Centre de Recherche du Centre Hospitalier de l’Universite Laval (CHUQ-CRCHUL), Universite Laval, Quebec City, Canada) ,  Gamu Daniel (Department of Kinesiology, University of Waterloo, Waterloo, Canada) ,  Fajardo Val A. (Department of Kinesiology, University of Waterloo, Waterloo, Canada) ,  Yagita Hideo (Department of Immunology, Juntendo University, School of Medicine, Tokyo, Japan) ,  Penninger Josef M. (IMBA, Institute of Molecular Biotechnology of the Austrian Academy of Sciences, Vienna, Austria) ,  Tupling A. Russell (Department of Kinesiology, University of Waterloo, Waterloo, Canada) ,  Frenette Jerome (Centre Hospitalier Universitaire de Quebec-Centre de Recherche du Centre Hospitalier de l’Universite Laval (CHUQ-CRCHUL), Universite Laval, Quebec City, Canada) ,  Frenette Jerome (Departement de Readaptation, Faculte de Medecine, Universite Laval, Quebec City, Canada)
Material： Acta Neuropathologica Communications (Web)
Volume： 6  Issue： 1  Page： 31  Publication year： 2018 
JST Material Number： U7296A  ISSN： 2051-5960  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Abstract/Point： Although there is a strong ass...

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Thesaurus term： *muscular dystrophy ,  skeletal muscle ,  dystrophin ,  antibody ,  receptor ,  mouse(animal) ,  interaction ,  *RANKL ,  osteoporosis ,  therapy ,  dysfunction ,  NF-kappaB ,  protective action
Semi thesaurus term： TNF関連アポトーシス誘導リガンド ,  *ジストロフィー , 【Automatic Indexing@JST】

Author keywords (4)： Osteoprotegerin ,  Skeletal muscle ,  SERCA ,  Duchenne muscular dystrophy

JST classification (1)： Basic medicine on musculoskeletal system  (GG01020B)

Reference (40)：

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• J Bone Miner Res Off J Am Soc Bone Miner Res; The effect of a single dose of osteoprotegerin in postmenopausal women; PJ Bekker, D Holloway, A Nakanishi, M Arrighi, PT Leese, CR Dunstan; 16; 2001; 348-360; 10.1359/jbmr.2001.16.2.348; citation_id=CR5

Terms in the title (7)： 筋ジストロフィー ,  緩和 ,  OPG ,  RANKL ,  筋肉 ,  阻害 ,  欠失