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J-GLOBAL ID：201902234585970388   Reference number：19A1479564

Exercise endurance capacity is markedly reduced due to impaired energy homeostasis during prolonged fasting in FABP4/5 deficient mice

運動持久力はFABP4/5欠損マウスにおける長期絶食時のエネルギー恒常性障害により著しく減少する【JST・京大機械翻訳】

Author (12)： Iso Tatsuya (Department of Cardiovascular Medicine, Gunma University Graduate School of Medicine, Maebashi, Japan) ,  Haruyama Hikari (Department of Laboratory Sciences, Gunma University Graduate School of Health Sciences, Maebashi, Japan) ,  Sunaga Hiroaki (Department of Cardiovascular Medicine, Gunma University Graduate School of Medicine, Maebashi, Japan) ,  Matsui Miki (Department of Cardiovascular Medicine, Gunma University Graduate School of Medicine, Maebashi, Japan) ,  Matsui Hiroki (Department of Laboratory Sciences, Gunma University Graduate School of Health Sciences, Maebashi, Japan) ,  Tanaka Rina (Department of Laboratory Sciences, Gunma University Graduate School of Health Sciences, Maebashi, Japan) ,  Umbarawan Yogi (Department of Cardiovascular Medicine, Gunma University Graduate School of Medicine, Maebashi, Japan) ,  Umbarawan Yogi (Department of Internal Medicine, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia) ,  Syamsunarno Mas Rizky A. A. (Department of Cardiovascular Medicine, Gunma University Graduate School of Medicine, Maebashi, Japan) ,  Syamsunarno Mas Rizky A. A. (Department of Biochemistry and Molecular Biology, Universitas Padjadjaran, Jatinangor, Indonesia) ,  Yokoyama Tomoyuki (Department of Laboratory Sciences, Gunma University Graduate School of Health Sciences, Maebashi, Japan) ,  Kurabayashi Masahiko (Department of Cardiovascular Medicine, Gunma University Graduate School of Medicine, Maebashi, Japan)
Material： BMC Physiology (Web)
Volume： 19  Issue： 1  Page： 1  Publication year： 2019 
JST Material Number： U7311A  ISSN： 1472-6793  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Abstract/Point： Skeletal muscle prefers carboh...

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Thesaurus term： genotype ,  glycogen ,  fatty acid ,  homeostasis ,  metabolism ,  motor capacity ,  *fasting ,  endothelium ,  treadmill ,  serum ,  skeletal muscle ,  heart ,  hexose ,  aldose
Semi thesaurus term： ランニング ,  *持久力 , 【Automatic Indexing@JST】

Author keywords (9)： Metabolism ,  Exercise ,  Fasting ,  Fatty acid ,  Glucose ,  Skeletal muscle ,  Liver ,  FABP4 ,  FABP5

JST classification (5)： Receptors on cell membrane  (EF04030C) ,  Gene expression  (EC02040Q) ,  Cell physiology in general  (EF02010S) ,  Biological function  (EB03040U) ,  Urogenital tumors(=neoplasms)  (GM04000S)

Substance index (1)： Glucose

Reference (36)：

• Nat Rev Endocrinol; Metabolic functions of FABPs--mechanisms and therapeutic implications; GS Hotamisligil, DA Bernlohr; 11; 2015; 592-605; 10.1038/nrendo.2015.122; citation_id=CR1
• Nat Rev Drug Discov; Fatty acid-binding proteins: role in metabolic diseases and potential as drug targets; M Furuhashi, GS Hotamisligil; 7; 2008; 489-503; 10.1038/nrd2589; citation_id=CR2
• Arterioscler Thromb Vasc Biol; Capillary endothelial fatty acid binding proteins 4 and 5 play a critical role in fatty acid uptake in heart and skeletal muscle; T Iso, K Maeda, H Hanaoka, T Suga, K Goto; 33; 2013; 2549-2557; 10.1161/ATVBAHA.113.301588; citation_id=CR3
• FASEB J; Fatty acid binding protein 4 is a target of VEGF and a regulator of cell proliferation in endothelial cells; H Elmasri, C Karaaslan, Y Teper, E Ghelfi, M Weng; 23; 2009; 3865-3873; 10.1096/fj.09-134882; citation_id=CR4
• Circ Res; Endothelial cells of the human microvasculature express epidermal fatty acid-binding protein; I Masouye, G Hagens, TH Kuppevelt, P Madsen, JH Saurat; 81; 1997; 297-303; 10.1161/01.RES.81.3.297; citation_id=CR5

Terms in the title (9)： 運動 ,  持久力 ,  FABP4 ,  欠損 ,  マウス ,  長期 ,  絶食 ,  エネルギー恒常性 ,  障害