Art

J-GLOBAL ID：201902234675933686   Reference number：19A0646631

ADAM-17 is expressed on rheumatoid arthritis fibroblast-like synoviocytes and regulates proinflammatory mediator expression and monocyte adhesion

ADAM-17は関節リウマチ線維芽細胞様滑膜細胞に発現し,炎症誘発性メディエーター発現と単球接着を調節する【JST・京大機械翻訳】

Author (7)： Ishii Sho (Division of Rheumatology, Department of Medicine, Showa University School of Medicine, Tokyo, Japan) ,  Isozaki Takeo (Division of Rheumatology, Department of Medicine, Showa University School of Medicine, Tokyo, Japan) ,  Furuya Hidekazu (Division of Rheumatology, Department of Medicine, Showa University School of Medicine, Tokyo, Japan) ,  Takeuchi Hiroko (Division of Rheumatology, Department of Medicine, Showa University School of Medicine, Tokyo, Japan) ,  Tsubokura Yumi (Division of Rheumatology, Department of Medicine, Showa University School of Medicine, Tokyo, Japan) ,  Inagaki Katsunori (Department of Orthopedic Surgery, Showa University School of Medicine, Tokyo, Japan) ,  Kasama Tsuyoshi (Division of Rheumatology, Department of Medicine, Showa University School of Medicine, Tokyo, Japan)
Material： Arthritis Research & Therapy (Web)
Volume： 20  Issue： 1  Page： 159  Publication year： 2018 
JST Material Number： U7412A  ISSN： 1478-6362  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Abstract/Point： To examine the expression of A...

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Thesaurus term： fluorescent antibody technique ,  osteoarthrosis ,  serum ,  inflammation mediator ,  *synovial membrane ,  siRNA ,  TNF alpha ,  transfection ,  *rheumatoid arthritis ,  cell adhesion ,  *adhesion(bond) ,  ELISA
Semi thesaurus term： ICAM-1 ,  細胞表面 ,  接着分子 , 【Automatic Indexing@JST】

Author keywords (4)： ADAM-17 ,  Rheumatoid arthritis ,  Cell adhesion ,  Cytokines

JST classification (2)： Basic medicine on musculoskeletal system  (GG01020B) ,  Musculoskeletal diseases  (GG03000T)

Reference (31)：

• Nature; Evolving concepts of rheumatoid arthritis; GS Firestein; 423; 6937; 2003; 356-361; 10.1038/nature01661; citation_id=CR1
• N Engl J Med; Cytokine pathways and joint inflammation in rheumatoid arthritis; EH Choy, GS Panayi; 344; 12; 2001; 907-916; 10.1056/NEJM200103223441207; citation_id=CR2
• Rheumatology (Oxford); Synovial fibroblasts: key players in rheumatoid arthritis; LC Huber, O Distler, I Tarner, RE Gay, S Gay, T Pap; 45; 6; 2006; 669-675; 10.1093/rheumatology/kel065; citation_id=CR3
• GMS Health Technol Assess; Influence of tumor necrosis factor alpha in rheumatoid arthritis; W Kulp, M Corzillus, W Greiner, L Pientka, U Siebert, JM von der Schulenburg; 1; 2005; Doc12; citation_id=CR4
• Curr Opin Rheumatol; Interleukin-6 in rheumatoid arthritis; N Nishimoto; 18; 3; 2006; 277-281; 10.1097/01.bor.0000218949.19860.d1; citation_id=CR5

Terms in the title (7)： ADAM ,  関節リウマチ ,  線維芽細胞様滑膜細胞 ,  発現 ,  炎症 ,  単球接着 ,  調節