Art

J-GLOBAL ID：201902236143452656   Reference number：19A1335365

The N-terminal sequence of murine PRMT5 variant 2 is required for Hsp70 interaction and CHIP ligase-mediated degradation

マウスPRMT5変異体2のN末端配列はHsp70相互作用とチップリガーゼ仲介分解に必要である【JST・京大機械翻訳】

Author (8)： Lu Weizhe (Ph.D. Program in Human Biology, School of Integrative Global Majors (SIGMA), University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, Japan) ,  Kim Jun-Dal (Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA), University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, Japan) ,  Tabara Saori (Graduate School of Life and Environmental Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, Japan) ,  Kwon Chulwon (Graduate School of Life and Environmental Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, Japan) ,  Mizukami Hayase (Graduate School of Life and Environmental Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, Japan) ,  Kimura Keiji (Graduate School of Life and Environmental Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, Japan) ,  Fukamizu Akiyoshi (Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA), University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, Japan) ,  Fukamizu Akiyoshi (International Institute for Integrative Sleep Medicine (WPI-IIIS), University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, Japan)
Material： Biochemical and Biophysical Research Communications  (BBRC)
Volume： 514  Issue： 4  Page： 1185-1191  Publication year： 2019 
JST Material Number： B0118A  ISSN： 0006-291X  Document type： Article
Article type： 短報  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Protein arginine methyltransfe...

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Thesaurus term： proteolysis ,  turnover ,  *Mus musculus ,  chaperone protein ,  symmetry ,  enzyme activity ,  *interaction ,  lysosome ,  Methylation ,  heat shock protein ,  database ,  polyubiquitination ,  C-terminal side ,  *PRMT5 ,  *Myomorpha ,  amino acid ,  aliphatic amine ,  aliphatic carboxylic acid ,  primary amine

Author keywords (5)： PRMT5 ,  Splice variants ,  NH2-terminus ,  Hsp70/CHIP ,  Protein degradation

JST classification (1)： Cell components in general  (EF03010Z)

Substance index (1)： Arginine

Terms in the title (9)： マウス ,  PRMT5 ,  変異体 ,  N末端配列 ,  HSP70 ,  相互作用 ,  リガーゼ ,  仲介 ,  分解