Art

J-GLOBAL ID：201902237608375117   Reference number：19A0148867

Conophylline suppresses pancreatic cancer desmoplasia and cancer-promoting cytokines produced by cancer-associated fibroblasts

コノフィリンは癌関連線維芽細胞により産生される膵臓癌線維形成と癌促進サイトカインを抑制する

Author (16)： Ishii Norihiro (Division of Hepatobiliary and Pancreatic Surgery, Department of General Surgical Science, Graduate School of Medicine, Gunma University, Maebashi, Japan) ,  Araki Kenichiro (Division of Hepatobiliary and Pancreatic Surgery, Department of General Surgical Science, Graduate School of Medicine, Gunma University, Maebashi, Japan) ,  Yokobori Takehiko (Research Program for Omics-based Medical Science, Division of Integrated Oncology Research, Gunma University Initiative for Advanced Research (GIAR), Maebashi, Japan) ,  Hagiwara Kei (Division of Hepatobiliary and Pancreatic Surgery, Department of General Surgical Science, Graduate School of Medicine, Gunma University, Maebashi, Japan) ,  Gantumur Dorgormaa (Division of Hepatobiliary and Pancreatic Surgery, Department of General Surgical Science, Graduate School of Medicine, Gunma University, Maebashi, Japan) ,  Yamanaka Takahiro (Division of Hepatobiliary and Pancreatic Surgery, Department of General Surgical Science, Graduate School of Medicine, Gunma University, Maebashi, Japan) ,  Handa Tadashi (Department of Diagnostic Pathology, Graduate School of Medicine, Gunma University, Maebashi, Japan) ,  Tsukagoshi Mariko (Division of Hepatobiliary and Pancreatic Surgery, Department of General Surgical Science, Graduate School of Medicine, Gunma University, Maebashi, Japan) ,  Igarashi Takamichi (Division of Hepatobiliary and Pancreatic Surgery, Department of General Surgical Science, Graduate School of Medicine, Gunma University, Maebashi, Japan) ,  Watanabe Akira (Division of Hepatobiliary and Pancreatic Surgery, Department of General Surgical Science, Graduate School of Medicine, Gunma University, Maebashi, Japan) ,  Kubo Norio (Division of Hepatobiliary and Pancreatic Surgery, Department of General Surgical Science, Graduate School of Medicine, Gunma University, Maebashi, Japan) ,  Harimoto Norifumi (Division of Hepatobiliary and Pancreatic Surgery, Department of General Surgical Science, Graduate School of Medicine, Gunma University, Maebashi, Japan) ,  Masamune Atsushi (Division of Gastroenterology, Graduate School of Medicine, Tohoku University, Sendai, Japan) ,  Umezawa Kazuo (Department of Molecular Target Medicine, Aichi Medical University School of Medicine, Nagakute, Japan) ,  Kuwano Hiroyuki (Division of Gastroenterological Surgery, Department of General Surgical Science, Graduate School of Medicine, Gunma University, Maebashi, Japan) ,  Shirabe Ken (Division of Hepatobiliary and Pancreatic Surgery, Department of General Surgical Science, Graduate School of Medicine, Gunma University, Maebashi, Japan)
Material： Cancer Science (Web)  (Cancer Sci (Web))
Volume： 110  Issue： 1  Page： 334-344  Publication year： 2019 
JST Material Number： U0505A  ISSN： 1349-7006  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： MCP-1 ,...
Semi thesaurus term： CXCL12 ,...

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Author keywords (5)： conophylline ,  cytokine ,  fibroblast ,  microenvironment ,  stellate cell

JST classification (2)： Basic research of antitumor(=antineoplastic)drugs  (GW16010A) ,  Experimental treatment for tumors  (GE02040Y)

Substance index (2)： Conophylline ,  Gemcitabine

Terms in the title (7)： コノフィリン ,  癌関連線維芽細胞 ,  膵臓癌 ,  線維形成 ,  癌 ,  促進 ,  サイトカイン