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J-GLOBAL ID：201902238324352188   Reference number：19A2369736

Fluorescent 1,4-Naphthoquinones To Visualize Diffuse and Dense-Core Amyloid Plaques in APP/PS1 Transgenic Mouse Brains

APP/PS1トランスジェニックマウス脳における拡散性および高密度コアアミロイド斑を可視化するための蛍光性1,4-ナフトキノン類【JST・京大機械翻訳】

Author (14)： Neo Shin Naewoo (Integrated Science and Engineering Division, Yonsei University, Republic of Korea) ,  Jeon Hanna (Department of Pharmacy and Yonsei Institute of Pharmaceutical Science, Yonsei University, Republic of Korea) ,  Jung Youngeun (Department of Pharmacy and Yonsei Institute of Pharmaceutical Science, Yonsei University, Republic of Korea) ,  Baek Seungyeop (Department of Pharmacy and Yonsei Institute of Pharmaceutical Science, Yonsei University, Republic of Korea) ,  Baek Seungyeop (Department of Biotechnology, Yonsei University, Republic of Korea) ,  Lee Sejin (Department of Pharmacy and Yonsei Institute of Pharmaceutical Science, Yonsei University, Republic of Korea) ,  Yoo Hee Chan (Department of Pharmacy and Yonsei Institute of Pharmaceutical Science, Yonsei University, Republic of Korea) ,  Bae Gi Hun (Department of Pharmacy and Yonsei Institute of Pharmaceutical Science, Yonsei University, Republic of Korea) ,  Park Keunwan (Natural Product Informatics Research Center, Korea Institute of Science and Technology, Republic of Korea) ,  Yang Seung-Hoon (Department of Medical Biotechnology, College of Life Science and Biotechnology, Dongguk University, Republic of Korea) ,  Han Jung Min (Department of Pharmacy and Yonsei Institute of Pharmaceutical Science, Yonsei University, Republic of Korea) ,  Kim Ikyon (Department of Pharmacy and Yonsei Institute of Pharmaceutical Science, Yonsei University, Republic of Korea) ,  Kim YoungSoo (Integrated Science and Engineering Division, Yonsei University, Republic of Korea) ,  Kim YoungSoo (Department of Pharmacy and Yonsei Institute of Pharmaceutical Science, Yonsei University, Republic of Korea)
Material： ACS Chemical Neuroscience
Volume： 10  Issue： 6  Page： 3031-3044  Publication year： 2019 
JST Material Number： W5038A  ISSN： 1948-7193  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： Recent clinical approvals of b...

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Thesaurus term： image processing ,  *visualization ,  human(primates) ,  contrast media ,  in vitro experiment ,  interaction ,  early diagnosis ,  *amyloid plaque ,  *transgenic mouse ,  Alzheimer disease ,  *amyloid ,  aggregation ,  aggregate ,  plaque ,  amyloid beta-protein ,  quinone ,  alicyclic compound ,  diene ,  polynuclear aromatic compound

Author keywords (6)： Alzheimer’s disease ,  amyloid ,  diffuse plaques ,  1 4-naphthoquinone ,  imaging agent ,  Aβ

JST classification (1)： Basic neurology  (GN01020W)

Substance index (1)： 1,4-Naphthoquinone

Terms in the title (10)： APP ,  トランスジェニックマウス ,  脳 ,  拡散性 ,  高密度 ,  コア ,  アミロイド斑 ,  可視化 ,  蛍光性 ,  ナフトキノン類