Art

J-GLOBAL ID：201902239411327325   Reference number：19A0445681

Nicotinamide alleviates kidney injury and pregnancy outcomes in lupus-prone MRL/lpr mice treated with lipopolysaccharide

ニコチンアミドはリポ多糖類で治療されたループス傾向MRL/lprマウスにおける腎臓損傷と妊娠転帰を緩和する【JST・京大機械翻訳】

Author (14)： Imaruoka Kenta (Division of Clinical Pharmacology and Therapeutics, Tohoku University Graduate School of Pharmaceutical Sciences & Faculty of Pharmaceutical Sciences, Sendai, 980-8578, Japan) ,  Oe Yuji (Division of Feto-Maternal Medical Science, Department of Community Medical Support, Tohoku Medical Megabank Organization, Tohoku University, Sendai, 980-8574, Japan) ,  Oe Yuji (Research Fellow of Japan Society for the Promotion of Science, Chiyoda-ku, Tokyo, 102-0083, Japan) ,  Fushima Tomofumi (Division of Clinical Pharmacology and Therapeutics, Tohoku University Graduate School of Pharmaceutical Sciences & Faculty of Pharmaceutical Sciences, Sendai, 980-8578, Japan) ,  Sato Emiko (Division of Clinical Pharmacology and Therapeutics, Tohoku University Graduate School of Pharmaceutical Sciences & Faculty of Pharmaceutical Sciences, Sendai, 980-8578, Japan) ,  Sato Emiko (Division of Nephrology, Endocrinology, and Vascular Medicine, Tohoku University Graduate School of Medicine, Sendai, 980-8574, Japan) ,  Sekimoto Akiyo (Division of Clinical Pharmacology and Therapeutics, Tohoku University Graduate School of Pharmaceutical Sciences & Faculty of Pharmaceutical Sciences, Sendai, 980-8578, Japan) ,  Sekimoto Akiyo (Division of Nephrology, Endocrinology, and Vascular Medicine, Tohoku University Graduate School of Medicine, Sendai, 980-8574, Japan) ,  Sato Hiroshi (Division of Clinical Pharmacology and Therapeutics, Tohoku University Graduate School of Pharmaceutical Sciences & Faculty of Pharmaceutical Sciences, Sendai, 980-8578, Japan) ,  Sato Hiroshi (Division of Nephrology, Endocrinology, and Vascular Medicine, Tohoku University Graduate School of Medicine, Sendai, 980-8574, Japan) ,  Sugawara Junichi (Division of Feto-Maternal Medical Science, Department of Community Medical Support, Tohoku Medical Megabank Organization, Tohoku University, Sendai, 980-8574, Japan) ,  Ito Sadayoshi (Division of Nephrology, Endocrinology, and Vascular Medicine, Tohoku University Graduate School of Medicine, Sendai, 980-8574, Japan) ,  Takahashi Nobuyuki (Division of Clinical Pharmacology and Therapeutics, Tohoku University Graduate School of Pharmaceutical Sciences & Faculty of Pharmaceutical Sciences, Sendai, 980-8578, Japan) ,  Takahashi Nobuyuki (Division of Nephrology, Endocrinology, and Vascular Medicine, Tohoku University Graduate School of Medicine, Sendai, 980-8574, Japan)
Material： Biochemical and Biophysical Research Communications  (BBRC)
Volume： 510  Issue： 4  Page： 587-593  Publication year： 2019 
JST Material Number： B0118A  ISSN： 0006-291X  Document type： Article
Article type： 短報  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Systemic lupus erythematosus (...

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Thesaurus term： *Pregnancy ,  oxidative stress ,  Glomerulonephritis ,  Inflammation ,  *lipopolysaccharide ,  parturition ,  systemic lupus erythematosus ,  Toll like receptor ,  Blood Pressure ,  *Mus musculus ,  Phenotype ,  mouse model ,  Signal Transduction ,  Pregnancy induced hypertensive nephropathy ,  *Myomorpha ,  nitrogen heterocyclic compound ,  drug ,  tobacco alkaloid
Semi thesaurus term： cellular signal transduction ,  子癇前症 , 【Automatic Indexing@JST】

Author keywords (5)： Systemic lupus erythematosus ,  Toll-like receptor 4 ,  Preterm birth ,  Fetal growth restriction ,  Inflammation

JST classification (4)： Development(=generation)and differentiation  (EJ16020W) ,  Gene expression  (EC02040Q) ,  Cell physiology in general  (EF02010S) ,  Receptors on cell membrane  (EF04030C)

Substance index (1)： Nicotine

Terms in the title (11)： ニコチンアミド ,  リポ多糖類 ,  治療 ,  ループス ,  傾向 ,  LPR ,  マウス ,  腎臓 ,  損傷 ,  妊娠転帰 ,  緩和