Art

J-GLOBAL ID：201902239763787824   Reference number：19A1565545

Simultaneous Control of Crystal Habit and Particle Size of Ecabet Sodium Hydrate with Rapid Cooling Crystallization and Temperature Cycling

急速冷却結晶化と温度サイクルによるエカベットナトリウム水和物の結晶晶癖と粒子サイズの同時制御

Author (6)： Kishida Muneki (Process Development Department, Production Technology & Supply Chain Management Division, Mitsubishi Tanabe Pharma Corporation) ,  Kishida Muneki (Department of Applied Chemistry and Bioengineering, Graduate School of Engineering, Osaka City University) ,  Igarashi Koichi (Department of Applied Chemistry and Bioengineering, Graduate School of Engineering, Osaka City University) ,  Azuma Masayuki (Department of Applied Chemistry and Bioengineering, Graduate School of Engineering, Osaka City University) ,  Ooshima Hiroshi (Department of Applied Chemistry and Bioengineering, Graduate School of Engineering, Osaka City University) ,  Ooshima Hiroshi (R&D Center, Kansai Chemical Engineering Co., Ltd.)
Material： Journal of Chemical Engineering of Japan  (J Chem Eng Jpn)
Volume： 52  Issue： 5  Page： 455-464(J-STAGE)  Publication year： 2019 
JST Material Number： S0629A  ISSN： 0021-9592  CODEN： JCEJAQ  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *crystallization ,  *heat cycle ,  hydrate ,  *crystal habit ,  *particle size (ratio) ,  shape control ,  rapid quenching ,  thickness ,  morphology ,  X-Ray Diffraction ,  scanning electron microscope ,  contact angle ,  servo control ,  carboxylic acid ,  sulfonic acid ,  olefin compound ,  polynuclear aromatic compound
Semi thesaurus term： thermal cycle ,  particle size ,  rapid quenching

Author keywords (6)： Particle Size ,  Particle Shape ,  Temperature Cycling ,  Particle Size ,  Particle Shape ,  Temperature Cycling

JST classification (2)： Crystal growth of organic compounds  (BK13070E) ,  Crystallization  (XD02070T)

Substance index (1)： Ecabet sodium

Reference (23)：

• Danjo, K., K. Kinoshita, K. Kitagawa, K. Iida, H. Sunada and A. Otsuka; “Effect of Particle Shape on the Compaction and Flow Properties of Powders,” Chem. Pharm. Bull., 37, 3070-3073 (1989)
• Di Martino, P., M. Beccerica, E. Joiris, G. F. Palmieri, A. Gayot and S. Martelli; “Influence of Crystal Habit on the Compression and Densification Mechanism of Ibuprofen,” J. Cryst. Growth, 243, 345-355 (2002)
• Grzymek, J.; “Control of the Exterior Form of Crystals during Crystallization,” Przemysl Chem., 21, 279-280 (1937)
• Heng, J. Y. Y., A. Bismarck and D. R. Williams; “Anisotropic Surface Chemistry of Crystalline Pharmaceutical Solids,” AAPS PharmSciTech, 7, E12-E20 (2006)
• Heng, J. Y. Y., A. Bismarck, A. F. Lee, K. Wilson and D. R. Williams; “Anisotropic Surface Chemistry of Aspirin Crystals,” J. Pharm. Sci., 96, 2134-2144 (2007)

Terms in the title (7)： 急速冷却 ,  結晶化 ,  温度サイクル ,  エカベットナトリウム ,  水和物 ,  結晶晶癖 ,  粒子サイズ