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J-GLOBAL ID：201902240185040749   Reference number：19A1109726

The Kiss Switch Brings Inactive R3C Ligase Ribozyme Back to Life

Kissスイッチは不活性なR3Cリガーゼのリボザイムを生命に戻す【JST・京大機械翻訳】

Author (6)： Tanizawa Kana (Department of Biological Science and Technology, Tokyo University of Science, 6-3-1 Niijuku, Katsushika-ku, Tokyo 125-8585, Japan) ,  Uchida Sayuri (Department of Biological Science and Technology, Tokyo University of Science, 6-3-1 Niijuku, Katsushika-ku, Tokyo 125-8585, Japan) ,  Kurihara Eri (Department of Biological Science and Technology, Tokyo University of Science, 6-3-1 Niijuku, Katsushika-ku, Tokyo 125-8585, Japan) ,  Umehara Takuya (Department of Biological Science and Technology, Tokyo University of Science, 6-3-1 Niijuku, Katsushika-ku, Tokyo 125-8585, Japan) ,  Tamura Koji (Department of Biological Science and Technology, Tokyo University of Science, 6-3-1 Niijuku, Katsushika-ku, Tokyo 125-8585, Japan) ,  Tamura Koji (Research Institute for Science and Technology, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba 278-8510, Japan)
Material： Biology (Web)
Volume： 7  Issue： 1  Page： 7  Publication year： 2018 
JST Material Number： U7145A  ISSN： 2079-7737  Document type： Article
Article type： 原著論文  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： R3C ligase ribozyme catalyzes ...

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Thesaurus term： triphosphoric acid ,  *ligase ,  catalyst ,  RNA ,  interaction ,  substrate (biochemistry) ,  switch ,  *ribozyme ,  substrate binding site ,  combining activity ,  phosphodiester bond
Semi thesaurus term： 再活性化 , 【Automatic Indexing@JST】

Author keywords (5)： R3C ligase ribozyme ,  kissing-loop interaction ,  activity ,  RNA switch ,  RNA world

JST classification (1)： Gene expression  (EC02040Q)

Reference (30)：

• Kruger, K.; Grabowski, P.J.; Zaug, A.J.; Sands, J.; Gottschling, D.E.; Cech, T.R. Self-splicing RNA: Autoexcision and autocyclization of the ribosomal RNA intervening sequence of Tetrahymena. Cell 1982, 31, 147-157.
• Guerrier-Takada, C.; Gardiner, K.; Marsh, T.; Pace, N.; Altman, S. The RNA moiety of ribonuclease P is the catalytic subunit of the enzyme. Cell 1983, 35, 849-857.
• Gilbert, W. Origin of life: The RNA world. Nature 1986, 319, 618.
• Illangasekare, M.; Sanchez, G.; Nickles, T.; Yarus, M. Aminoacyl-RNA synthesis catalyzed by an RNA. Science 1995, 267, 643-647.
• Kumar, R.K.; Yarus, M. RNA-catalyzed amino acid activation. Biochemistry 2001, 40, 6998-7004.

Terms in the title (4)： 不活性 ,  リガーゼ ,  リボザイム ,  生命