Art
J-GLOBAL ID:201902241051169434   Reference number:19A0199219

Inhibition of the STAT5/Pim Kinase Axis Enhances Cytotoxic Effects of Proteasome Inhibitors on FLT3-ITD-Positive AML Cells by Cooperatively Inhibiting the mTORC1/4EBP1/S6K/Mcl-1 Pathway

STAT5/PIMキナーゼAxisの阻害はmTORC1/4EBP1/S6K/MCL-1経路を協同的に阻害することによりFLT3-ITD陽性AML細胞に対するプロテアソーム阻害剤の細胞毒性効果を増強する【JST・京大機械翻訳】
Author (7):
Material:
Volume: 12  Issue:Page: 336-349  Publication year: 2019 
JST Material Number: W2898A  ISSN: 1936-5233  Document type: Article
Article type: 原著論文  Country of issue: Netherlands (NLD)  Language: ENGLISH (EN)
Abstract/Point:
Abstract/Point
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FLT3-ITD and FLT3-TKD are the ...
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Clinical application of antitumor(=antineoplastic)drugs  ,  Basic research of antitumor(=antineoplastic)drugs 
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