Art

J-GLOBAL ID：201902241686682848   Reference number：19A0069032

Hydrophilic scaffolds of oxime as the potent catalytic inactivator of reactive organophosphate

反応性有機リン酸塩の強力な触媒不活性化剤としてのオキシムの親水性足場【JST・京大機械翻訳】

Author (14)： Tang Shengzhuang (Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI 48109, United States) ,  Tang Shengzhuang (Michigan Nanotechnology Institute for Medicine and Biological Sciences, University of Michigan Medical School, Ann Arbor, MI 48109, United States) ,  Wong Pamela T. (Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI 48109, United States) ,  Wong Pamela T. (Michigan Nanotechnology Institute for Medicine and Biological Sciences, University of Michigan Medical School, Ann Arbor, MI 48109, United States) ,  Cannon Jayme (Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI 48109, United States) ,  Cannon Jayme (Michigan Nanotechnology Institute for Medicine and Biological Sciences, University of Michigan Medical School, Ann Arbor, MI 48109, United States) ,  Yang Kelly (Michigan Nanotechnology Institute for Medicine and Biological Sciences, University of Michigan Medical School, Ann Arbor, MI 48109, United States) ,  Bowden Sierra (Michigan Nanotechnology Institute for Medicine and Biological Sciences, University of Michigan Medical School, Ann Arbor, MI 48109, United States) ,  Bhattacharjee Somnath (Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI 48109, United States) ,  Bhattacharjee Somnath (Michigan Nanotechnology Institute for Medicine and Biological Sciences, University of Michigan Medical School, Ann Arbor, MI 48109, United States) ,  O'Konek Jessica J. (Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI 48109, United States) ,  O'Konek Jessica J. (Michigan Nanotechnology Institute for Medicine and Biological Sciences, University of Michigan Medical School, Ann Arbor, MI 48109, United States) ,  Choi Seok Ki (Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI 48109, United States) ,  Choi Seok Ki (Michigan Nanotechnology Institute for Medicine and Biological Sciences, University of Michigan Medical School, Ann Arbor, MI 48109, United States)
Material： Chemico-Biological Interactions  (Chem Biol Interact)
Volume： 297  Page： 67-79  Publication year： 2019 
JST Material Number： H0058B  ISSN： 0009-2797  CODEN： CBINA  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Despite its efficacy as a skin...

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Thesaurus term： acetylcholinesterase ,  screening(inspection) ,  *hydrophilicity ,  optimization ,  effectiveness ,  therapy ,  lead compound ,  *reactivity ,  *oxime ,  half-life ,  acidity(degree) ,  polarity ,  catalytic activity ,  electric charge
Semi thesaurus term： 汚染除去 , 【Automatic Indexing@JST】

Author keywords (5)： Reactive organophosphate ,  Dekon 139 ,  Oxime ,  Skin decontamination ,  Acetylcholine esterase

JST classification (2)： Antidotes  (GZ04020B) ,  Organop phosphorus compounds  (CF08040N)

Terms in the title (6)： 反応性 ,  有機リン酸塩 ,  触媒不活性化 ,  オキシム ,  親水性 ,  足場