Art

J-GLOBAL ID：201902242931592863   Reference number：19A0798778

Acute administration of ketamine attenuates the impairment of social behaviors induced by social defeat stress exposure as juveniles via activation of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors

ケタミンの急性投与は,α-アミノ-3-ヒドロキシ-5-メチル-4-イソオキサゾールプロピオン酸(AMPA)受容体の活性化を介して,幼生としての社会的デフェットストレス曝露によって誘発される社会的行動の障害を軽減する【JST・京大機械翻訳】

Author (17)： Hasegawa Sho (Division of Clinical Sciences and Neuropsychopharmacology, Faculty and Graduate School of Pharmacy, Meijo University, Nagoya, Japan) ,  Yoshimi Akira (Division of Clinical Sciences and Neuropsychopharmacology, Faculty and Graduate School of Pharmacy, Meijo University, Nagoya, Japan) ,  Mouri Akihiro (Department of Regulatory Science for Evaluation and Development of Pharmaceuticals and Devices, Graduate School of Health Sciences, Fujita Health University, Aichi, Japan) ,  Mouri Akihiro (Japanese Drug Organization of Appropriate Use and Research, Nagoya, Japan) ,  Uchida Yoji (Division of Clinical Sciences and Neuropsychopharmacology, Faculty and Graduate School of Pharmacy, Meijo University, Nagoya, Japan) ,  Hida Hirotake (Division of Clinical Sciences and Neuropsychopharmacology, Faculty and Graduate School of Pharmacy, Meijo University, Nagoya, Japan) ,  Hida Hirotake (Department of Neuropsychopharmacology and Hospital Pharmacy, Graduate School of Medicine, Nagoya University, Nagoya, Japan) ,  Mishina Masayoshi (Brain Science Laboratory, The Research Organization of Science and Technology, Ritsumeikan University, Shiga, Japan) ,  Yamada Kiyofumi (Department of Neuropsychopharmacology and Hospital Pharmacy, Graduate School of Medicine, Nagoya University, Nagoya, Japan) ,  Yamada Kiyofumi (Japanese Drug Organization of Appropriate Use and Research, Nagoya, Japan) ,  Ozaki Norio (Department of Psychiatry, Graduate School of Medicine, Nagoya University, Nagoya, Japan) ,  Nabeshima Toshitaka (Advanced Diagnostic System Research Laboratory, Graduate School of Health Sciences, Fujita Health University, Aichi, Japan) ,  Nabeshima Toshitaka (Japanese Drug Organization of Appropriate Use and Research, Nagoya, Japan) ,  Noda Yukihiro (Division of Clinical Sciences and Neuropsychopharmacology, Faculty and Graduate School of Pharmacy, Meijo University, Nagoya, Japan) ,  Noda Yukihiro (Department of Neuropsychopharmacology and Hospital Pharmacy, Graduate School of Medicine, Nagoya University, Nagoya, Japan) ,  Noda Yukihiro (Department of Psychiatry, Graduate School of Medicine, Nagoya University, Nagoya, Japan) ,  Noda Yukihiro (Japanese Drug Organization of Appropriate Use and Research, Nagoya, Japan)
Material： Neuropharmacology
Volume： 148  Page： 107-116  Publication year： 2019 
JST Material Number： H0537A  ISSN： 0028-3908  CODEN： NEPHBW  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： The impairment of social behav...

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Thesaurus term： *subunit ,  antipsychotic agent ,  psychotic disorder ,  Eumetopias jubata ,  NMDA receptor ,  AMPA receptor ,  phosphorylation ,  antidepressive drug ,  juvenile ,  GluN2B ,  *acute administration ,  amino acid ,  aliphatic amine ,  aliphatic carboxylic acid ,  dicarboxylic acid ,  secondary amine ,  nitrogen heterocyclic compound ,  phenolic compound ,  diol ,  secondary alcohol ,  aromatic chlorine compound ,  alicyclic ketone
Semi thesaurus term： アンタゴニスト , 【Automatic Indexing@JST】

Author keywords (6)： Social defeat stress ,  Juvenile ,  Social behaviors ,  Ketamine ,  NMDA receptor ,  AMPA receptor

JST classification (2)： Receptors on cell membrane  (EF04030C) ,  Basic neurology  (GN01020W)

Substance index (3)： NMDA ,  Ifenprodil ,  Ketamine

Terms in the title (13)： ケタミン ,  急性投与 ,  イソオキサゾール ,  プロピオン酸 ,  AMPA ,  受容体 ,  活性化 ,  幼生 ,  社会 ,  曝露 ,  誘発 ,  社会的行動 ,  障害