Art

J-GLOBAL ID：201902243378006650   Reference number：19A2185573

Clinical Safety and Efficacy of Secondary Prophylactic Pegylated G-CSF in Advanced Pancreatic Cancer Patients Treated with mFOLFIRINOX: A Single-center Retrospective Study

mFOLFIRINOXで治療した進行膵臓癌患者における二次予防的PEG化G-CSFの臨床安全性と有効性:単一施設後向き研究

Author (16)： Yamao Kentaro (Department of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Japan) ,  Takenaka Mamoru (Department of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Japan) ,  Yoshikawa Tomoe (Department of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Japan) ,  Ishikawa Rei (Department of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Japan) ,  Okamoto Ayana (Department of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Japan) ,  Yamazaki Tomohiro (Department of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Japan) ,  Nakai Atsushi (Department of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Japan) ,  Omoto Shunsuke (Department of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Japan) ,  Kamata Ken (Department of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Japan) ,  Minaga Kosuke (Department of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Japan) ,  Hagiwara Satoru (Department of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Japan) ,  Sakurai Toshiharu (Department of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Japan) ,  Nishida Naoshi (Department of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Japan) ,  Chiba Yasutaka (Clinical Research Center, Kindai University Hospital, Japan) ,  Watanabe Tomohiro (Department of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Japan) ,  Kudo Masatoshi (Department of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Japan)
Material： Internal Medicine (Web)  (Intern Med (Web))
Volume： 58  Issue： 14  Page： 1993-2002(J-STAGE)  Publication year： 2019 
JST Material Number： U0033A  ISSN： 1349-7235  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： human(primates) ,...
Semi thesaurus term： mFOLFIRINOX療法 ,...

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Author keywords (3)： pegylated G-CSF ,  mFOLFIRINOX ,  pancreatic cancer

JST classification (2)： Drug therapy(=pharmacotherapy)for tumors  (GE03032C) ,  Tumors(=neoplasms)of digestive system  (GH04000D)

Substance index (3)： Fluorouracil ,  Irinotecan ,  Levoleucovorin

Reference (49)：

• 1. Egawa S, Toma H, Ohigashi H, et al. Japan Pancreatic Cancer Registry; 30th year anniversary: Japan Pancreas Society. Pancreas 41: 985-992, 2012.
• 2. Conroy T, Desseigne F, Ychou M, et al. FOLFIRINOX versus gemcitabine for metastatic pancreatic cancer. N Engl J Med 364: 1817-1825, 2011.
• 3. National Cancer Institute Common Terminology Criteria for Adverse Events v. https://evs.nci.nih.gov/ftp1/CTCAE/CTCAE_4.03/CTCAE_4.03_2010-06-14_QuickReference_5x7.pdf
• 4. Okusaka T, Ikeda M, Fukutomi A, et al. Phase II study of FOLFIRINOX for chemotherapy-naive Japanese patients with metastatic pancreatic cancer. Cancer Sci 105: 1321-1326, 2014.
• 5. Chllamma MK, Cook N, Dhani NC, et al. FOLFIRINOX for advanced pancreatic cancer: the Princess Margaret Cancer Centre experience. Br J Cancer 115: 649-654, 2016.

Terms in the title (11)： 治療 ,  進行膵臓癌 ,  患者 ,  二次予防 ,  PEG化 ,  G-CSF ,  臨床 ,  安全性 ,  有効性 ,  施設 ,  研究