Art

J-GLOBAL ID：201902243985482700   Reference number：19A1751380

Comparison of mRNA expression profiles of drug-metabolizing enzymes and transporters in fresh and cryopreserved cynomolgus monkey hepatocytes

新鮮および凍結保存カニクイザル肝細胞における薬物代謝酵素および輸送体のmRNA発現プロファイルの比較

Author (11)： Koeda Akiko (Ina Research Inc., Ina, Japan) ,  Koeda Akiko (Department of Clinical Pharmacy, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya, Japan) ,  Iwao Takahiro (Department of Clinical Pharmacy, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya, Japan) ,  Iwao Takahiro (Educational Research Center for Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Nagoya City University, Nagoya, Japan) ,  Nakanishi Anna (Educational Research Center for Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Nagoya City University, Nagoya, Japan) ,  Mizuno Shota (Educational Research Center for Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Nagoya City University, Nagoya, Japan) ,  Yamashita Misaki (Educational Research Center for Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Nagoya City University, Nagoya, Japan) ,  Sakai Yoko (Department of Clinical Pharmacy, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya, Japan) ,  Nakamura Katsunori (Department of Pharmacy, Ryukyu University Hospital, Okinawa, Japan) ,  Matsunaga Tamihide (Department of Clinical Pharmacy, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya, Japan) ,  Matsunaga Tamihide (Educational Research Center for Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Nagoya City University, Nagoya, Japan)
Material： Drug Metabolism and Pharmacokinetics (Web)  (Drug Metab Pharmacokinet (Web))
Volume： 34  Issue： 4  Page： 253-263  Publication year： 2019 
JST Material Number： U0705A  ISSN： 1347-4367  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： Macaca fascicularis ,...
Semi thesaurus term： mRNA expression ,...

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Author keywords (8)： Co-culture ,  Cynomolgus monkey ,  Drug-metabolizing enzymes ,  Hepatocytes ,  Monolayer ,  mRNA expression profiles ,  Spheroid ,  Transporters

JST classification (1)： Cell and tissue culture methods  (EA03040R)

Terms in the title (7)： 凍結保存 ,  カニクイザル ,  肝細胞 ,  薬物代謝酵素 ,  輸送体 ,  mRNA発現 ,  プロファイル