Art

J-GLOBAL ID：201902244267144719   Reference number：19A2523318

Recombinant thrombomodulin prevented hepatic ischemia-reperfusion injury by inhibiting high-mobility group box 1 in rats

組換えトロンボモジュリンはラットにおける高移動性グループボックス1阻害により肝虚血-再潅流障害を予防する【JST・京大機械翻訳】

Author (10)： Hirakawa Yuki (Department of Hepatology, Kanazawa Medical University, Uchinada, Ishikawa, 920-0293, Japan) ,  Tsuchishima Mutsumi (Department of Hepatology, Kanazawa Medical University, Uchinada, Ishikawa, 920-0293, Japan) ,  Fukumura Atsushi (Department of Hepatology, Kanazawa Medical University, Uchinada, Ishikawa, 920-0293, Japan) ,  Kinoshita Kaori (Department of Hepatology, Kanazawa Medical University, Uchinada, Ishikawa, 920-0293, Japan) ,  Hayashi Nobuhiko (Department of Hepatology, Kanazawa Medical University, Uchinada, Ishikawa, 920-0293, Japan) ,  Saito Takashi (Department of Hepatology, Kanazawa Medical University, Uchinada, Ishikawa, 920-0293, Japan) ,  George Joseph (Department of Hepatology, Kanazawa Medical University, Uchinada, Ishikawa, 920-0293, Japan) ,  Toshikuni Nobuyuki (Department of Hepatology, Kanazawa Medical University, Uchinada, Ishikawa, 920-0293, Japan) ,  Ueda Yoshimichi (Department of Pathology II, Kanazawa Medical University, Uchinada, Ishikawa, 920-0293, Japan) ,  Tsutsumi Mikihiro (Department of Hepatology, Kanazawa Medical University, Uchinada, Ishikawa, 920-0293, Japan)
Material： European Journal of Pharmacology  (Eur J Pharmacol)
Volume： 863  Page： Null  Publication year： 2019 
JST Material Number： B0841A  ISSN： 0014-2999  CODEN： EJPHAZ  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Recombinant thrombomodulin (rT...

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Thesaurus term： hepatic dysfunction ,  blood flow ,  serum concentration ,  *ischemia ,  *reperfusion ,  body weight ,  *rat ,  portal vein ,  TNF alpha ,  antiphlogistic ,  anticoagulant ,  protective action
Semi thesaurus term： 有害事象 ,  *再潅流障害 ,  *肝虚血 , 【Automatic Indexing@JST】

Author keywords (5)： Ischemia ,  Ischemia-reperfusion injury ,  Recombinant-thrombomodulin ,  HMGB1 ,  4-Hydroxynonenal

JST classification (3)： Basic medicine on cardiovascular system  (GJ01020K) ,  Basic research of addictive analgesics and narcotics  (GW03080Z) ,  Basic research of psychotropic drugs  (GW03100Y)

Terms in the title (8)： 組換えトロンボモジュリン ,  ラット ,  移動性 ,  グループ ,  ボックス ,  阻害 ,  虚血-再潅流障害 ,  予防