Art

J-GLOBAL ID：201902244362488918   Reference number：19A1494122

Ten Years of Tau-Targeted Immunotherapy: The Path Walked and the Roads Ahead

タウ標的免疫療法の10年 道の道と道【JST・京大機械翻訳】

Author (8)： Novak Petr (Institute of Neuroimmunology, Slovak Academy of Sciences, Bratislava, Slovakia) ,  Novak Petr (AXON Neuroscience CRM Services SE, Bratislava, Slovakia) ,  Kontsekova Eva (Institute of Neuroimmunology, Slovak Academy of Sciences, Bratislava, Slovakia) ,  Kontsekova Eva (AXON Neuroscience R&D Services SE, Bratislava, Slovakia) ,  Zilka Norbert (Institute of Neuroimmunology, Slovak Academy of Sciences, Bratislava, Slovakia) ,  Zilka Norbert (AXON Neuroscience R&D Services SE, Bratislava, Slovakia) ,  Novak Michal (Institute of Neuroimmunology, Slovak Academy of Sciences, Bratislava, Slovakia) ,  Novak Michal (AXON Neuroscience SE, Larnaca, Cyprus)
Material： Frontiers in Neuroscience (Web)
Volume： 12  Page： 798  Publication year： 2018 
JST Material Number： U7087A  ISSN： 1662-453X  Document type： Article
Article type： 文献レビュー  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Neurofibrillary pathology comp...

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Thesaurus term： pathological state ,  pathophysiology ,  phenotype ,  human(primates) ,  epitope ,  characterization ,  temporal lobe ,  cortex(animal tissue) ,  *immunotherapy ,  vaccine ,  antibody ,  nerve fiber ,  Alzheimer disease
Semi thesaurus term： 動物モデル ,  認知障害 ,  神経変性疾患 , 【Automatic Indexing@JST】

Author keywords (5)： tau ,  immunotherapy ,  neurofibrillary degeneration ,  clinical trials ,  animal models

JST classification (2)： Basic neurology  (GN01020W) ,  Nervous system diseases  (GN03000O)

Reference (139)：

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• Alzheimer A. (1907). Über eine eigenartige Erkrankung der Hirnrinde. Allgemeine Z. Psychiatr. Psychisch Gerichtliche Med. 64 146-148. doi: 10.1016/j.jalz.2015.06.1884
• Arif M., Kazim S. F., Grundke-Iqbal I., Garruto R. M., Iqbal K. (2014). Tau pathology involves protein phosphatase 2A in parkinsonism-dementia of Guam. Proc. Natl. Acad. Sci. U.S.A. 111 1144-1149. doi: 10.1073/pnas.1322614111
• Armstrong M. J., et al (2013). Criteria for the diagnosis of corticobasal degeneration. Neurology 80 496-503. doi: 10.1073/pnas.1322614111
• Audouard E., Houben S., Masaracchia C., Yilmaz Z., Suain V., Authelet M., et al (2016). High-molecular-weight paired helical filaments from alzheimer brain induces seeding of wild-type mouse Tau into an Argyrophilic 4R Tau Pathology in vivo. Am. J. Pathol. 186 2709-2722. doi: 10.1016/j.ajpath.2016.06.008

Terms in the title (3)： 標的 ,  免疫療法 ,  道