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J-GLOBAL ID：201902245003597166   Reference number：19A1066982

Bioactivity, Health Benefits, and Related Molecular Mechanisms of Curcumin: Current Progress, Challenges, and Perspectives

クルクミンの生物活性,健康利益及び関連する分子機構:現在の進歩,挑戦及び展望【JST・京大機械翻訳】

Author (7)： Xu Xiao-Yu (Department of Nutrition, School of Public Health, Sun Yat-Sen University, Guangzhou 510080, China) ,  Meng Xiao (Department of Nutrition, School of Public Health, Sun Yat-Sen University, Guangzhou 510080, China) ,  Li Sha (School of Chinese Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong 999077, China) ,  Gan Ren-You (Department of Food Science & Technology, School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai 200240, China) ,  Li Ya (Department of Nutrition, School of Public Health, Sun Yat-Sen University, Guangzhou 510080, China) ,  Li Hua-Bin (Department of Nutrition, School of Public Health, Sun Yat-Sen University, Guangzhou 510080, China) ,  Li Hua-Bin (South China Sea Bioresource Exploitation and Utilization Collaborative Innovation Center, Sun Yat-Sen University, Guangzhou 510006, China)
Material： Nutrients (Web)
Volume： 10  Issue： 10  Page： 1553  Publication year： 2018 
JST Material Number： U7255A  ISSN： 2072-6643  Document type： Article
Article type： 文献レビュー  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Curcumin is a principal curcum...

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Thesaurus term： functional food ,  coloring matter ,  pharmacology ,  antioxidation ,  diabetes mellitus ,  human(primates) ,  Curcuma longa ,  clinical trial ,  protective action ,  anti-inflammatory action ,  metabolism ,  *biological activity ,  diene ,  phenolic compound ,  phenol ether ,  enone ,  diketone
Semi thesaurus term： *分子機構 ,  *健康 , 【Automatic Indexing@JST】

Author keywords (7)： curcumin ,  gut metabolism ,  health benefits ,  antioxidant ,  anticancer ,  anti-inflammatory ,  molecular mechanisms

JST classification (3)： Basic research of pharmacology of crude drugs  (GX06020J) ,  Fruits and processed fruit products  (FJ11030Z) ,  Food chemistry,nutritional value  (FJ01020J)

Substance index (1)： Curcumin

Reference (203)：

• Maheshwari, R.K.; Singh, A.K.; Gaddipati, J.; Srimal, R.C. Multiple biological activities of curcumin: A short review. Life Sci. 2006, 78, 2081-2087.
• Nelson, K.M.; Dahlin, J.L.; Bisson, J.; Graham, J.; Pauli, G.F.; Walters, M.A. The essential medicinal chemistry of curcumin. J. Med. Chem. 2017, 60, 1620-1637.
• Awasthi, M.; Singh, S.; Pandey, V.P.; Dwivedi, U.N. Curcumin: Structure-activity relationship towards its role as a versatile multi-targeted therapeutics. Mini Rev. Org. Chem. 2017, 14, 311-332.
• Wang, R.; Li, J.B.; Zhao, Y.L.; Li, Y.P.; Yin, L. Investigating the therapeutic potential and mechanism of curcumin in breast cancer based on RNA sequencing and bioinformatics analysis. Breast Cancer 2018, 25, 206-212.
• Cao, J.; Wang, T.; Wang, M. Investigation of the anti-cataractogenic mechanisms of curcumin through in vivo and in vitro studies. BMC Ophthalmol. 2018, 18, 48.

Terms in the title (5)： クルクミン ,  生物活性 ,  利益 ,  分子 ,  展望