Art

J-GLOBAL ID：201902245782367548   Reference number：19A1496424

Glycans as Key Checkpoints of T Cell Activity and Function

T細胞活性と機能の重要なチェックポイントとしてのグリカン【JST・京大機械翻訳】

Author (27)： Pereira Marcia S. (Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP) Porto, Portugal) ,  Pereira Marcia S. (Institute for Research and Innovation in Health (I3S) Porto, Portugal) ,  Pereira Marcia S. (Institute of Biomedical Sciences of Abel Salazar, University of Porto Porto, Portugal) ,  Alves Ines (Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP) Porto, Portugal) ,  Alves Ines (Institute for Research and Innovation in Health (I3S) Porto, Portugal) ,  Alves Ines (Medical Faculty, University of Porto Porto, Portugal) ,  Vicente Manuel (Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP) Porto, Portugal) ,  Vicente Manuel (Institute for Research and Innovation in Health (I3S) Porto, Portugal) ,  Vicente Manuel (Institute of Biomedical Sciences of Abel Salazar, University of Porto Porto, Portugal) ,  Campar Ana (Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP) Porto, Portugal) ,  Campar Ana (Institute for Research and Innovation in Health (I3S) Porto, Portugal) ,  Campar Ana (Institute of Biomedical Sciences of Abel Salazar, University of Porto Porto, Portugal) ,  Campar Ana (Centro Hospitalar do Porto Porto, Portugal) ,  Silva Mariana C. (Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP) Porto, Portugal) ,  Silva Mariana C. (Institute for Research and Innovation in Health (I3S) Porto, Portugal) ,  Padrao Nuno A. (Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP) Porto, Portugal) ,  Padrao Nuno A. (Institute for Research and Innovation in Health (I3S) Porto, Portugal) ,  Padrao Nuno A. (Medical Faculty, University of Porto Porto, Portugal) ,  Pinto Vanda (Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP) Porto, Portugal) ,  Pinto Vanda (Institute for Research and Innovation in Health (I3S) Porto, Portugal) ,  Fernandes Angela (Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP) Porto, Portugal) ,  Fernandes Angela (Institute for Research and Innovation in Health (I3S) Porto, Portugal) ,  Dias Ana M. (Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP) Porto, Portugal) ,  Dias Ana M. (Institute for Research and Innovation in Health (I3S) Porto, Portugal) ,  Pinho Salome S. (Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP) Porto, Portugal) ,  Pinho Salome S. (Institute for Research and Innovation in Health (I3S) Porto, Portugal) ,  Pinho Salome S. (Medical Faculty, University of Porto Porto, Portugal)
Material： Frontiers in Immunology (Web)
Volume： 9  Page： 2754  Publication year： 2018 
JST Material Number： U7074A  ISSN： 1664-3224  Document type： Article
Article type： 文献レビュー  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： The immune system is highly co...

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Thesaurus term： differentiation(biology) ,  *T cell ,  pathophysiology ,  immunological tolerance ,  receptor ,  glycosylation ,  pathogen ,  autoimmunity ,  pathogenesis ,  interaction
Semi thesaurus term： 調節因子 ,  適応免疫 ,  免疫細胞 ,  免疫系 ,  *グリカン , 【Automatic Indexing@JST】

Author keywords (6)： N-glycosylation ,  glycans ,  T cells ,  immune response ,  autoimmunity ,  self-tolerance

JST classification (1)： Immunological reaction in general  (ED03010T)

Reference (136)：

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• Vasta GR, Feng C, González-Montalbán N, Mancini J, Yang L, Abernathy K, et al. Functions of galectins as 'self/non-self'-recognition and effector factors. Pathog Dis. (2017) 75:ftx046. doi: 10.1093/femspd/ftx046
• Brown GD, Willment JA, Whitehead L. C-type lectins in immunity and homeostasis. Nat Rev Immunol. (2018) 18:374-89. doi: 10.1038/s41577-018-0004-8
• Macauley MS, Crocker PR, Paulson JC. Siglec-mediated regulation of immune cell function in disease. Nat Rev Immunol. (2014) 14:653-66. doi: 10.1038/nri3737
• Bochner BS, Zimmermann N. Role of siglecs and related glycan-binding proteins in immune responses and immunoregulation. J Allergy Clin Immunol. (2015) 135:598-608. doi: 10.1016/j.jaci.2014.11.031

Terms in the title (4)： T細胞 ,  活性 ,  チェックポイント ,  グリカン