Art

J-GLOBAL ID：201902246020229851   Reference number：19A1420285

Loss of fibrocystin promotes interleukin-8-dependent proliferation and CTGF production of biliary epithelium

フィブロシスチンの消失は胆管上皮のインターロイキン8依存性増殖とCTGF産生を促進する【JST・京大機械翻訳】

Author (24)： Tsunoda Tomoyuki (Department of Gastroenterology and Hepatology, Tokyo Medical and Dental University (TMDU), Tokyo, Japan) ,  Kakinuma Sei (Department of Gastroenterology and Hepatology, Tokyo Medical and Dental University (TMDU), Tokyo, Japan) ,  Kakinuma Sei (Department of Liver Disease Control, Tokyo Medical and Dental University (TMDU), Tokyo, Japan) ,  Miyoshi Masato (Department of Gastroenterology and Hepatology, Tokyo Medical and Dental University (TMDU), Tokyo, Japan) ,  Kamiya Akihide (Department of Molecular Life Sciences, School of Medicine, Tokai University, Isehara, Japan) ,  Kaneko Shun (Department of Gastroenterology and Hepatology, Tokyo Medical and Dental University (TMDU), Tokyo, Japan) ,  Sato Ayako (Department of Gastroenterology and Hepatology, Tokyo Medical and Dental University (TMDU), Tokyo, Japan) ,  Tsuchiya Jun (Department of Gastroenterology and Hepatology, Tokyo Medical and Dental University (TMDU), Tokyo, Japan) ,  Nitta Sayuri (Department of Gastroenterology and Hepatology, Tokyo Medical and Dental University (TMDU), Tokyo, Japan) ,  Kawai-Kitahata Fukiko (Department of Gastroenterology and Hepatology, Tokyo Medical and Dental University (TMDU), Tokyo, Japan) ,  Murakawa Miyako (Department of Gastroenterology and Hepatology, Tokyo Medical and Dental University (TMDU), Tokyo, Japan) ,  Itsui Yasuhiro (Department of Gastroenterology and Hepatology, Tokyo Medical and Dental University (TMDU), Tokyo, Japan) ,  Nakagawa Mina (Department of Gastroenterology and Hepatology, Tokyo Medical and Dental University (TMDU), Tokyo, Japan) ,  Azuma Seishin (Department of Gastroenterology and Hepatology, Tokyo Medical and Dental University (TMDU), Tokyo, Japan) ,  Sogo Tsuyoshi (Department of Pediatric Hepatology and Gastroenterology, Saiseikai Yokohamashi Tobu Hospital, Yokohama, Japan) ,  Komatsu Haruki (Department of Pediatrics, Toho University Sakura Medical Center, Sakura, Japan) ,  Mukouchi Ryutaro (Department of Pathology, Saiseikai Yokohamashi Tobu Hospital, Yokohama, Japan) ,  Inui Ayano (Department of Pediatric Hepatology and Gastroenterology, Saiseikai Yokohamashi Tobu Hospital, Yokohama, Japan) ,  Fujisawa Tomoo (Department of Pediatric Hepatology and Gastroenterology, Saiseikai Yokohamashi Tobu Hospital, Yokohama, Japan) ,  Nakauchi Hiromitsu (Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, USA) ,  Nakauchi Hiromitsu (Division of Stem Cell Therapy, Institute of Medical Science, The University of Tokyo, Tokyo, Japan) ,  Asahina Yasuhiro (Department of Gastroenterology and Hepatology, Tokyo Medical and Dental University (TMDU), Tokyo, Japan) ,  Asahina Yasuhiro (Department of Liver Disease Control, Tokyo Medical and Dental University (TMDU), Tokyo, Japan) ,  Watanabe Mamoru (Department of Gastroenterology and Hepatology, Tokyo Medical and Dental University (TMDU), Tokyo, Japan)
Material： Journal of Hepatology  (J Hepatol)
Volume： 71  Issue： 1  Page： 143-152  Publication year： 2019 
JST Material Number： A0278C  ISSN： 0168-8278  CODEN： JOHEEC  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Congenital hepatic fibrosis (C...

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Thesaurus term： RNA ,  clone ,  Heredity ,  dysfunction ,  *epithelium ,  pathogenesis ,  human ,  *bile duct ,  gene ,  Proteins ,  in vitro experiment ,  versatility ,  culture (biology) ,  *interleukin 8 ,  Mutation ,  *membrane and film ,  *histomembrane

Author keywords (8)： Polycystic kidney and hepatic disease 1 ,  PKHD1 ,  Fibrocystin ,  Congenital hepatic fibrosis ,  Human induced pluripotent stem cells ,  Hepatic progenitor-like cells ,  Ductal plate malformation ,  Liver transplantation

JST classification (1)： Cell physiology in general  (EF02010S)

Terms in the title (7)： 胆管 ,  上皮 ,  インターロイキン8 ,  依存性 ,  増殖 ,  CTGF ,  促進