Art

J-GLOBAL ID：201902247768258360   Reference number：19A2862736

Vitamin K3 derivative induces apoptotic cell death in neuroblastoma via downregulation of MYCN expression

ビタミンK3誘導体はMYCN発現のダウンレギュレーションを介して神経芽細胞腫におけるアポトーシス細胞死を誘導する【JST・京大機械翻訳】

Author (7)： Yoda Hiroyuki (Laboratory of Clinical Medicine, School of Pharmacy, Nihon University, 7-7-1 Narashinodai, Funabashi, Chiba, 274-8555, Japan) ,  Nakayama Toshimitsu (Center for Pharmacist Education, School of Pharmacy, Nihon University, 7-7-1 Narashinodai, Funabashi, Chiba, 274-8555, Japan) ,  Miura Motofumi (Laboratory of Molecular Chemistry, School of Pharmacy, Nihon University, 7-7-1 Narashinodai, Funabashi, Chiba, 274-8555, Japan) ,  Toriyama Masaharu (Laboratory of Molecular Chemistry, School of Pharmacy, Nihon University, 7-7-1 Narashinodai, Funabashi, Chiba, 274-8555, Japan) ,  Motohashi Shigeyasu (Laboratory of Molecular Chemistry, School of Pharmacy, Nihon University, 7-7-1 Narashinodai, Funabashi, Chiba, 274-8555, Japan) ,  Suzuki Takashi (Laboratory of Clinical Medicine, School of Pharmacy, Nihon University, 7-7-1 Narashinodai, Funabashi, Chiba, 274-8555, Japan) ,  Suzuki Takashi (Department of Pediatrics and Child Health, School of Medicine, Nihon University, 30-1 Oyaguchikami, Itabashi-ku, Tokyo, 173-0032, Japan)
Material： Biochemistry and Biophysics Reports
Volume： 20  Page： Null  Publication year： 2019 
JST Material Number： W3090A  ISSN： 2405-5808  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Neuroblastoma is a pediatric m...

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Thesaurus term： *neuroblastoma ,  *neuroblast ,  p53 protein ,  *apoptosis ,  antitumor action ,  therapeutic planning ,  *down-regulation ,  mRNA ,  sympathetic nerve system ,  cell proliferation
Semi thesaurus term： 過剰発現 ,  Mcl-1 ,  抗アポトーシス作用 ,  BCL-2 ,  *MYCN , 【Automatic Indexing@JST】

Author keywords (6)： Vitamin K3 ,  Neuroblastoma ,  Bcl-2 ,  Mcl-1 ,  MYCN ,  LIN28B

JST classification (1)： Cell physiology in general  (EF02010S)

Terms in the title (8)： ビタミンK3 ,  誘導体 ,  MYCN ,  発現 ,  ダウンレギュレーション ,  神経芽細胞腫 ,  アポトーシス細胞死 ,  誘導