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J-GLOBAL ID：201902248083670076   Reference number：19A1303630

Anti-inflammatory effects of naturally occurring retinoid X receptor agonists isolated from Sophora tonkinensis Gagnep. via retinoid X receptor/liver X receptor heterodimers

Sophora tonkinensis Gagnep.から単離した天然に存在するレチノイドX受容体作動薬のレチノイドX受容体/肝臓X受容体ヘテロ二量体を介した抗炎症効果

Author (4)： Wang Wei (Department of Pharmacology of Natural Compounds, Graduate School of Pharmaceutical Sciences, Aichi Gakuin University, Nagoya, Japan) ,  Nakashima Ken-ichi (Department of Pharmacology of Natural Compounds, Graduate School of Pharmaceutical Sciences, Aichi Gakuin University, Nagoya, Japan) ,  Hirai Takao (Department of Pharmacology of Natural Compounds, Graduate School of Pharmaceutical Sciences, Aichi Gakuin University, Nagoya, Japan) ,  Inoue Makoto (Department of Pharmacology of Natural Compounds, Graduate School of Pharmaceutical Sciences, Aichi Gakuin University, Nagoya, Japan)
Material： Journal of Natural Medicines  (J Nat Med)
Volume： 73  Issue： 2  Page： 419-430  Publication year： 2019 
JST Material Number： L5856A  ISSN： 1340-3443  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Thesaurus term： transcription factor ,...
Semi thesaurus term： *Sophora tonkinensis ,...

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Author keywords (6)： Activating transcription factor 3 ,  Antiinflammation ,  Liver X receptor ,  Naturally occurring agonist ,  Retinoid X receptor ,  RXR/LXR heterodimer

JST classification (4)： Basic research of pharmacology of crude drugs  (GX06020J) ,  Other natural substances of biological origin  (CF10090R) ,  Plant biochemistry  (EH01050J) ,  Gene expression  (EC02040Q)

Substance index (5)： SPF-1 ,  SPF-2 ,  T-0901317 ,  Sophoranone ,  LGD-1069

Terms in the title (6)： 単離 ,  レチノイドX受容体 ,  作動薬 ,  肝臓X受容体 ,  ヘテロ二量体 ,  抗炎症効果