Art

J-GLOBAL ID：201902248422033040   Reference number：19A0528451

Glucocorticoid receptor suppresses gene expression of Rev-erbα (Nr1d1) through interaction with the CLOCK complex

グルココルチコイド受容体は時計複合体との相互作用を介してRev-erbBα(NR1D1)の遺伝子発現を抑制する【JST・京大機械翻訳】

Author (32)： Murayama Yuki (Nutrigenomics Research Group, Faculty of Medicine, University of Tsukuba, Japan) ,  Murayama Yuki (Department of Internal Medicine (Endocrinology and Metabolism), Faculty of Medicine, University of Tsukuba, Japan) ,  Yahagi Naoya (Nutrigenomics Research Group, Faculty of Medicine, University of Tsukuba, Japan) ,  Yahagi Naoya (Department of Internal Medicine (Endocrinology and Metabolism), Faculty of Medicine, University of Tsukuba, Japan) ,  Takeuchi Yoshinori (Nutrigenomics Research Group, Faculty of Medicine, University of Tsukuba, Japan) ,  Takeuchi Yoshinori (Department of Internal Medicine (Endocrinology and Metabolism), Faculty of Medicine, University of Tsukuba, Japan) ,  Aita Yuichi (Nutrigenomics Research Group, Faculty of Medicine, University of Tsukuba, Japan) ,  Aita Yuichi (Department of Internal Medicine (Endocrinology and Metabolism), Faculty of Medicine, University of Tsukuba, Japan) ,  Mehrazad Saber Zahra (Nutrigenomics Research Group, Faculty of Medicine, University of Tsukuba, Japan) ,  Mehrazad Saber Zahra (Department of Internal Medicine (Endocrinology and Metabolism), Faculty of Medicine, University of Tsukuba, Japan) ,  Wada Nobuhiro (Nutrigenomics Research Group, Faculty of Medicine, University of Tsukuba, Japan) ,  Li EnXu (Nutrigenomics Research Group, Faculty of Medicine, University of Tsukuba, Japan) ,  Piao Xianying (Nutrigenomics Research Group, Faculty of Medicine, University of Tsukuba, Japan) ,  Sawada Yoshikazu (Nutrigenomics Research Group, Faculty of Medicine, University of Tsukuba, Japan) ,  Shikama Akito (Nutrigenomics Research Group, Faculty of Medicine, University of Tsukuba, Japan) ,  Shikama Akito (Department of Internal Medicine (Endocrinology and Metabolism), Faculty of Medicine, University of Tsukuba, Japan) ,  Masuda Yukari (Nutrigenomics Research Group, Faculty of Medicine, University of Tsukuba, Japan) ,  Nishi-Tatsumi Makiko (Nutrigenomics Research Group, Faculty of Medicine, University of Tsukuba, Japan) ,  Kubota Midori (Nutrigenomics Research Group, Faculty of Medicine, University of Tsukuba, Japan) ,  Izumida Yoshihiko (Nutrigenomics Research Group, Faculty of Medicine, University of Tsukuba, Japan) ,  Miyamoto Takafumi (Department of Internal Medicine (Endocrinology and Metabolism), Faculty of Medicine, University of Tsukuba, Japan) ,  Sekiya Motohiro (Department of Internal Medicine (Endocrinology and Metabolism), Faculty of Medicine, University of Tsukuba, Japan) ,  Matsuzaka Takashi (Department of Internal Medicine (Endocrinology and Metabolism), Faculty of Medicine, University of Tsukuba, Japan) ,  Nakagawa Yoshimi (Department of Internal Medicine (Endocrinology and Metabolism), Faculty of Medicine, University of Tsukuba, Japan) ,  Sugano Yoko (Department of Internal Medicine (Endocrinology and Metabolism), Faculty of Medicine, University of Tsukuba, Japan) ,  Iwasaki Hitoshi (Department of Internal Medicine (Endocrinology and Metabolism), Faculty of Medicine, University of Tsukuba, Japan) ,  Kobayashi Kazuto (Department of Internal Medicine (Endocrinology and Metabolism), Faculty of Medicine, University of Tsukuba, Japan) ,  Yatoh Shigeru (Department of Internal Medicine (Endocrinology and Metabolism), Faculty of Medicine, University of Tsukuba, Japan) ,  Suzuki Hiroaki (Department of Internal Medicine (Endocrinology and Metabolism), Faculty of Medicine, University of Tsukuba, Japan) ,  Yagyu Hiroaki (Department of Internal Medicine (Endocrinology and Metabolism), Faculty of Medicine, University of Tsukuba, Japan) ,  Kawakami Yasushi (Department of Internal Medicine (Endocrinology and Metabolism), Faculty of Medicine, University of Tsukuba, Japan) ,  Shimano Hitoshi (Department of Internal Medicine (Endocrinology and Metabolism), Faculty of Medicine, University of Tsukuba, Japan)
Material： FEBS Letters  (for the Rapid Publication of Short Reports in Biochemistry, Biophysics)
Volume： 593  Issue： 4  Page： 423-432  Publication year： 2019 
JST Material Number： D0575A  ISSN： 0014-5793  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： Glucocorticoids have various m...

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Thesaurus term： promoter (genetics) ,  clock gene ,  *glucocorticoid receptor ,  DNA ,  *gene expression ,  side effect ,  control circuit ,  *interaction ,  *glucocorticoid ,  diurnal rhythm ,  *complex (substance) ,  BMAL1 ,  E box ,  *molecular genetic phenomenon
Semi thesaurus term： 抑制効果 , 【Automatic Indexing@JST】

Author keywords (5)： circadian rhythm ,  clock ,  glucocorticoid receptor ,  glucocorticoids ,  tethering

JST classification (3)： Receptors on cell membrane  (EF04030C) ,  Biological function  (EB03040U) ,  Cell physiology in general  (EF02010S)

Terms in the title (6)： グルココルチコイド受容体 ,  時計 ,  複合体 ,  相互作用 ,  ErbB ,  遺伝子発現