Art

J-GLOBAL ID：201902248675239181   Reference number：19A0968841

Hydrogel-Based Drug Delivery Nanosystems for the Treatment of Brain Tumors

脳腫瘍の治療のためのヒドロゲルに基づくドラッグデリバリーナノシステム【JST・京大機械翻訳】

Author (12)： Basso Joao (Faculty of Pharmacy, University of Coimbra, Coimbra 3000-354, Portugal) ,  Basso Joao (Center for Neurosciences and Cell Biology (CNC), University of Coimbra, Coimbra 3004-504, Portugal) ,  Miranda Ana (Faculty of Pharmacy, University of Coimbra, Coimbra 3000-354, Portugal) ,  Miranda Ana (Center for Neurosciences and Cell Biology (CNC), University of Coimbra, Coimbra 3004-504, Portugal) ,  Nunes Sandra (Coimbra Chemistry Centre, Department of Chemistry, University of Coimbra, Coimbra 3004-535, Portugal) ,  Cova Tania (Coimbra Chemistry Centre, Department of Chemistry, University of Coimbra, Coimbra 3004-535, Portugal) ,  Sousa Joao (Faculty of Pharmacy, University of Coimbra, Coimbra 3000-354, Portugal) ,  Sousa Joao (LAQV REQUIMTE, Group of Pharmaceutical Technology, Porto 4051-401, Portugal) ,  Vitorino Carla (Faculty of Pharmacy, University of Coimbra, Coimbra 3000-354, Portugal) ,  Vitorino Carla (Center for Neurosciences and Cell Biology (CNC), University of Coimbra, Coimbra 3004-504, Portugal) ,  Vitorino Carla (LAQV REQUIMTE, Group of Pharmaceutical Technology, Porto 4051-401, Portugal) ,  Pais Alberto (Coimbra Chemistry Centre, Department of Chemistry, University of Coimbra, Coimbra 3004-535, Portugal)
Material： Gels (Web)
Volume： 4  Issue： 3  Page： 62  Publication year： 2018 
JST Material Number： U7193A  ISSN： 2310-2861  Document type： Article
Article type： 文献レビュー  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Chemotherapy is commonly assoc...

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Thesaurus term： safety ,  nanostructure ,  targeting ,  effectiveness ,  *hydrogel ,  drug therapy ,  antitumor drug ,  side effect ,  *brain tumor ,  nano particle ,  *drug delivery system ,  tumor cell ,  effect
Semi thesaurus term： ナノゲル ,  特異性 , 【Automatic Indexing@JST】

Author keywords (6)： hydrogel ,  nanostructured drug delivery system ,  hydrogel nanoparticles ,  glioblastoma ,  drug delivery ,  local treatment

JST classification (2)： Basic biopharmacy  (GY01021U) ,  Basic research of antitumor(=antineoplastic)drugs  (GW16010A)

Reference (127)：

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• Nobusawa, S.; Watanabe, T.; Kleihues, P.; Ohgaki, H. IDH1 Mutations as Molecular Signature and Predictive Factor of Secondary Glioblastomas. Clin. Cancer Res. 2009, 15, 6002-6007.
• Yan, H.; Parsons, D.W.; Jin, G.; McLendon, R.; Rasheed, B.A.; Yuan, W.; Kos, I.; Batinic-Haberle, I.; Jones, S.; Riggins, G.J.; et al. IDH1 and IDH2 Mutations in Gliomas. N. Engl. J. Med. 2009, 360, 765-773.
• Juratli, T.A.; Schackert, G.; Krex, D. Current Status of Local Therapy in Malignant Gliomas-A Clinical Review of Three Selected Approaches. Pharmacol. Ther. 2013, 139, 341-358.
• Wolinsky, J.B.; Colson, Y.L.; Grinstaff, M.W. Local drug delivery strategies for cancer treatment: Gels, nanoparticles, polymeric films, rods, and wafers. J. Control. Release 2012, 159, 14-26.

Terms in the title (3)： 脳腫瘍 ,  治療 ,  ヒドロゲル