Art

J-GLOBAL ID：201902248795430184   Reference number：19A1803085

The Use of Fluoroproline in MUC1 Antigen Enables Efficient Detection of Antibodies in Patients with Prostate Cancer

MUC1抗原におけるフルオロプロリンの使用は前立腺癌患者における抗体の効率的検出を可能にする【JST・京大機械翻訳】

Author (21)： Somovilla Victor J. (Departamento de Quimica, Universidad de La Rioja, Centro de Investigacion en Sintesis Quimica, Spain) ,  Somovilla Victor J. (Department of Chemical Biology and Drug Discovery, Utrecht Institute for Pharmaceutical Sciences, Bijvoet Center for Biomolecular Research, Utrecht University, The Netherlands) ,  Bermejo Iris A. (Departamento de Quimica, Universidad de La Rioja, Centro de Investigacion en Sintesis Quimica, Spain) ,  Albuquerque Ines S. (Instituto de Medicina Molecular, Faculdade de Medicina da, Universidade de Lisboa, Portugal) ,  Martinez-Saez Nuria (Departamento de Quimica, Universidad de La Rioja, Centro de Investigacion en Sintesis Quimica, Spain) ,  Martinez-Saez Nuria (Department of Chemical Biology and Drug Discovery, Utrecht Institute for Pharmaceutical Sciences, Bijvoet Center for Biomolecular Research, Utrecht University, The Netherlands) ,  Castro-Lopez Jorge (Institute of Biocomputation and Physics of Complex Systems (BIFI), University of Zaragoza, BIFI-IQFR (CSIC), Spain) ,  Garcia-Martin Fayna (Graduate School and Faculty of Advanced Life Science, Field of Drug Discovery Research, Hokkaido University, Japan) ,  Companon Ismael (Departamento de Quimica, Universidad de La Rioja, Centro de Investigacion en Sintesis Quimica, Spain) ,  Hinou Hiroshi (Graduate School and Faculty of Advanced Life Science, Field of Drug Discovery Research, Hokkaido University, Japan) ,  Nishimura Shin-Ichiro (Graduate School and Faculty of Advanced Life Science, Field of Drug Discovery Research, Hokkaido University, Japan) ,  Jimenez-Barbero Jesus ((i) CIC bioGUNE, Bizkaia Technology Park, Building 801A, 48170 Derio, Spain; (ii) Ikerbasque, Basque Foundation for Science, Maria Diaz de Haro 13, 48009 Bilbao, Spain; (iii) Department of Organic Chemistry II, Faculty of Science & Technology, University of the Basque Country, Spain) ,  Asensio Juan L. (Instituto de Quimica Organica General, IQOG-CSIC, Spain) ,  Avenoza Alberto (Departamento de Quimica, Universidad de La Rioja, Centro de Investigacion en Sintesis Quimica, Spain) ,  Busto Jesus H. (Departamento de Quimica, Universidad de La Rioja, Centro de Investigacion en Sintesis Quimica, Spain) ,  Hurtado-Guerrero Ramon (Institute of Biocomputation and Physics of Complex Systems (BIFI), University of Zaragoza, BIFI-IQFR (CSIC), Spain) ,  Hurtado-Guerrero Ramon (Fundacion ARAID, Spain) ,  Peregrina Jesus M. (Departamento de Quimica, Universidad de La Rioja, Centro de Investigacion en Sintesis Quimica, Spain) ,  Bernardes Goncalo J. L. (Instituto de Medicina Molecular, Faculdade de Medicina da, Universidade de Lisboa, Portugal) ,  Bernardes Goncalo J. L. (Department of Chemistry, University of Cambridge, U.K.) ,  Corzana Francisco (Departamento de Quimica, Universidad de La Rioja, Centro de Investigacion en Sintesis Quimica, Spain)
Material： Journal of the American Chemical Society  (J Am Chem Soc)
Volume： 139  Issue： 50  Page： 18255-18261  Publication year： 2017 
JST Material Number： C0254A  ISSN： 0002-7863  CODEN： JACSAT  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： A structure-based design of a ...

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Thesaurus term： diagnosis ,  serum ,  *antibody ,  affinity ,  glycopeptide ,  peptide ,  *antigen ,  simulation ,  immunogenicity ,  antigen-antibody complex ,  *prostatic tumor ,  X-ray crystallography ,  fluorination
Semi thesaurus term： 残基 ,  *ムチン-1 , 【Automatic Indexing@JST】

JST classification (3)： Urogenital tumors(=neoplasms)  (GM04000S) ,  Basic research of antitumor(=antineoplastic)drugs  (GW16010A) ,  Basic research of immunotherapeutic agents and blood preparations  (GW22010D)

Terms in the title (5)： MUC1 ,  抗原 ,  前立腺 ,  癌患者 ,  抗体