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J-GLOBAL ID:201902249203322865   Reference number:19A1567302

A natural anti-periodontitis agent, epimedokoreanin B, inhibits virulence activities of gingipains from Porphyromonas gingivalis

天然の抗歯周炎剤,epimedokoreanin BはPorphyromonas gingivalis由来ギンギパイン類の病原活性を阻害する
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Volume: 83  Issue:Page: 1382-1384  Publication year: Jul. 2019 
JST Material Number: G0021A  ISSN: 0916-8451  CODEN: BBBIEJ  Document type: Article
Article type: 短報  Country of issue: United Kingdom (GBR)  Language: ENGLISH (EN)
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Basic dentistry(= odontology)  ,  Basic research of other drugs 
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Reference (18):
  • Slots J. Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis in periodontal disease: introduction. Periodontol 2000. 1999;20:7-13.
  • Oliver RC, Brown LJ. Periodontal diseases and tooth loss. Periodontol 2000. 1993;2:117-127.
  • Imamura T. The role of gingipains in the pathogenesis of periodontal disease. J Periodontol. 2003;74:111-118.
  • O’Brien-Simpson NM, Veith PD, Dashper SG, et al. Porphyromonas gingivalis gingipains: the molecular teeth of a microbial vampire. Curr Protein Pept Sci. 2003;4:409-426.
  • Potempa J, Sroka A, Imamura T, et al. Gingipains, the major cysteine proteinases and virulence factors of Porphyromonas gingivalis: structure, function and assembly of multidomain protein complexes. Current Protein Pept Sci. 2003;4:397-407.
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