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J-GLOBAL ID：201902249746642715   Reference number：19A2852463

Endogenous Calcitonin Gene-Related Peptide Deficiency Exacerbates Postoperative Lymphedema by Suppressing Lymphatic Capillary Formation and M2 Macrophage Accumulation

内因性カルシトニン遺伝子関連ペプチド欠乏はリンパ毛細管形成とM2マクロファージ蓄積を抑制することにより術後リンパ浮腫を悪化させる【JST・京大機械翻訳】

Author (23)： Matsui Shuhei (Department of Cardiovascular Research, Shinshu University School of Medicine, Japan) ,  Matsui Shuhei (Department of Anesthesiology, Shinshu University School of Medicine, Japan) ,  Tanaka Megumu (Department of Cardiovascular Research, Shinshu University School of Medicine, Japan) ,  Kamiyoshi Akiko (Department of Cardiovascular Research, Shinshu University School of Medicine, Japan) ,  Kamiyoshi Akiko (Department of Life Innovation, Institute for Biomedical Sciences, Interdisciplinary Cluster for Cutting Edge Research, Shinshu University, Matsumoto, Nagano, Japan) ,  Sakurai Takayuki (Department of Cardiovascular Research, Shinshu University School of Medicine, Japan) ,  Sakurai Takayuki (Department of Life Innovation, Institute for Biomedical Sciences, Interdisciplinary Cluster for Cutting Edge Research, Shinshu University, Matsumoto, Nagano, Japan) ,  Ichikawa-Shindo Yuka (Department of Cardiovascular Research, Shinshu University School of Medicine, Japan) ,  Kawate Hisaka (Department of Cardiovascular Research, Shinshu University School of Medicine, Japan) ,  Dai Kun (Department of Cardiovascular Research, Shinshu University School of Medicine, Japan) ,  Cui Nanqi (Department of Cardiovascular Research, Shinshu University School of Medicine, Japan) ,  Wei Yangxuan (Department of Cardiovascular Research, Shinshu University School of Medicine, Japan) ,  Tanaka Masaaki (Department of Cardiovascular Research, Shinshu University School of Medicine, Japan) ,  Tanaka Masaaki (Department of Ophthalmology, Shinshu University School of Medicine, Matsumoto, Nagano, Japan) ,  Kakihara Shinji (Department of Cardiovascular Research, Shinshu University School of Medicine, Japan) ,  Kakihara Shinji (Department of Ophthalmology, Shinshu University School of Medicine, Matsumoto, Nagano, Japan) ,  Nakamura Keisei (Department of Cardiovascular Research, Shinshu University School of Medicine, Japan) ,  Yamauchi Akihiro (Department of Cardiovascular Research, Shinshu University School of Medicine, Japan) ,  Ishida Kumiko (Department of Anesthesiology, Shinshu University School of Medicine, Japan) ,  Tanaka Satoshi (Department of Anesthesiology, Shinshu University School of Medicine, Japan) ,  Kawamata Mikito (Department of Anesthesiology, Shinshu University School of Medicine, Japan) ,  Shindo Takayuki (Department of Cardiovascular Research, Shinshu University School of Medicine, Japan) ,  Shindo Takayuki (Department of Life Innovation, Institute for Biomedical Sciences, Interdisciplinary Cluster for Cutting Edge Research, Shinshu University, Matsumoto, Nagano, Japan)
Material： American Journal of Pathology  (Am J Pathol)
Volume： 189  Issue： 12  Page： 2487-2502  Publication year： 2019 
JST Material Number： E0065B  ISSN： 0002-9440  CODEN： AJPAA  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Lymphedema is a chronic condit...

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Thesaurus term： *peptide ,  *calcitonin ,  pain ,  alternative splicing ,  endothelium ,  *lymphatic edema ,  *calcitonin gene related peptide ,  down-regulation ,  *lymph ,  capillary vessel ,  sensory nerve ,  *edema ,  *gene ,  lymph duct ,  pathophysiology

JST classification (4)： Biological function  (EB03040U) ,  Enzyme in general  (EB09010D) ,  Cell physiology in general  (EF02010S) ,  Basic medicine on cardiovascular system  (GJ01020K)

Terms in the title (9)： 内因性 ,  カルシトニン遺伝子関連ペプチド ,  欠乏 ,  リンパ ,  毛細管 ,  M2マクロファージ ,  蓄積 ,  リンパ浮腫 ,  悪化