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J-GLOBAL ID：201902250198118363   Reference number：19A1777735

Long noncoding RNA UCA1 enhances sensitivity to oncolytic vaccinia virus by sponging miR-18a/miR-182 and modulating the Cdc42/filopodia axis in colorectal cancer

長鎖非コードRNA UCA1は結腸直腸癌においてmiR-18A/miR-182をスポンジングし,Cdc42/Filopodia軸を調節することにより腫瘍溶解性ワクシニアウイルスに対する感受性を増強する【JST・京大機械翻訳】

Author (6)： Horita Kosuke (Division of Molecular Medicine, Department of Biomedical Science, Graduate School of Medical Sciences, Tottori University, 86 Nishi-cho, Yonago, 683-8503, Japan) ,  Kurosaki Hajime (Division of Molecular Medicine, Department of Biomedical Science, Graduate School of Medical Sciences, Tottori University, 86 Nishi-cho, Yonago, 683-8503, Japan) ,  Nakatake Motomu (Division of Molecular Medicine, Department of Biomedical Science, Graduate School of Medical Sciences, Tottori University, 86 Nishi-cho, Yonago, 683-8503, Japan) ,  Ito Mai (Division of Molecular Medicine, Department of Biomedical Science, Graduate School of Medical Sciences, Tottori University, 86 Nishi-cho, Yonago, 683-8503, Japan) ,  Kono Hiromichi (Division of Molecular Medicine, Department of Biomedical Science, Graduate School of Medical Sciences, Tottori University, 86 Nishi-cho, Yonago, 683-8503, Japan) ,  Nakamura Takafumi (Division of Molecular Medicine, Department of Biomedical Science, Graduate School of Medical Sciences, Tottori University, 86 Nishi-cho, Yonago, 683-8503, Japan)
Material： Biochemical and Biophysical Research Communications  (BBRC)
Volume： 516  Issue： 3  Page： 831-838  Publication year： 2019 
JST Material Number： B0118A  ISSN： 0006-291X  Document type： Article
Article type： 短報  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： The promising anti-tumor effec...

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Thesaurus term： ovarian tumor ,  Drug Resistance ,  *sensitivity ,  *Vaccinia virus ,  function analysis ,  antitumor action ,  *tumor ,  Up-Regulation ,  MicroRNAs ,  molecular mechanism ,  *RNA, Untranslated ,  *Long Untranslated RNA ,  *microorganism ,  *Poxviridae
Semi thesaurus term： 悪性腫瘍 ,  *結腸直腸癌 , 【Automatic Indexing@JST】

Author keywords (5)： Oncolytic vaccinia virus ,  Biomarker ,  UCA1 ,  miRNA ,  Cdc42

JST classification (2)： Cell physiology in general  (EF02010S) ,  Biological function  (EB03040U)

Terms in the title (9)： 長鎖非コードRNA ,  結腸直腸癌 ,  Cdc42 ,  調節 ,  腫瘍 ,  溶解性 ,  ワクシニアウイルス ,  感受性 ,  増強