Art

J-GLOBAL ID：201902250361805720   Reference number：19A1473363

Chromatin Regulation by HP1γ Contributes to Survival of 5-Azacytidine-Resistant Cells

HP1γによるクロマチン調節は5-アザシチジン耐性細胞の生存に寄与する【JST・京大機械翻訳】

Author (6)： Imanishi Satoshi (Institute of Medical Science, Tokyo Medical University, Tokyo, Japan) ,  Umezu Tomohiro (Institute of Medical Science, Tokyo Medical University, Tokyo, Japan) ,  Kobayashi Chiaki (Institute of Medical Science, Tokyo Medical University, Tokyo, Japan) ,  Ohta Tomohiko (Department of Translational Oncology, St. Marianna University Graduate School of Medicine, Kawasaki, Japan) ,  Ohyashiki Kazuma (Department of Hematology, Tokyo Medical University, Tokyo, Japan) ,  Ohyashiki Junko H. (Institute of Medical Science, Tokyo Medical University, Tokyo, Japan)
Material： Frontiers in Pharmacology (Web)
Volume： 9  Page： 1166  Publication year： 2018 
JST Material Number： U7091A  ISSN： 1663-9812  Document type： Article
Article type： 原著論文  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Recent investigations of the t...

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Thesaurus term： Methylation ,  *chromatin ,  Down-Regulation ,  human ,  Leukemia ,  sensitivity ,  tumor ,  Apoptosis ,  Proteins ,  targeting ,  hemopoiesis ,  bromodomain ,  histone modification ,  ribonucleoside
Semi thesaurus term： 阻害剤 , 【Automatic Indexing@JST】

Author keywords (6)： drug resistance ,  azacytidine ,  histone modification ,  heterochromatin protein 1 ,  bromodomain inhibitor ,  leukemia

JST classification (4)： Gene expression  (EC02040Q) ,  Cell physiology in general  (EF02010S) ,  Immunologic diseases,allergic diseases in general.  (GD04010C) ,  Basic research of antitumor(=antineoplastic)drugs  (GW16010A)

Substance index (1)： Azacitidine

Reference (29)：

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• Fuks F., Hurd P. J., Deplus R., Kouzarides T. (2003). The DNA methyltransferases associate with HP1 and the SUV39H1 histone methyltransferase. Nucleic Acids Res. 31 2305-2312. doi: 10.1093/nar/gkg332

Terms in the title (7)： HP1γ ,  クロマチン ,  調節 ,  5-アザシチジン ,  耐性 ,  細胞 ,  生存