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J-GLOBAL ID：201902251800728301   Reference number：19A1280096

Hepatocyte Growth Factor Activator: A Proteinase Linking Tissue Injury with Repair

肝細胞増殖因子活性化因子:修復を伴う組織損傷を連結するプロテイナーゼ【JST・京大機械翻訳】

Author (4)： Fukushima Tsuyoshi (Section of Oncopathology and Regenerative Biology, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyotake 889-1692, Miyazaki, Japan) ,  Uchiyama Shuichiro (Department of Surgery, Miyakonojyo Medical Association Hospital, 1364-1 Tarobocho, Miyakonojyo 885-0002, Miyazaki, Japan) ,  Tanaka Hiroyuki (Section of Oncopathology and Regenerative Biology, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyotake 889-1692, Miyazaki, Japan) ,  Kataoka Hiroaki (Section of Oncopathology and Regenerative Biology, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyotake 889-1692, Miyazaki, Japan)
Material： International Journal of Molecular Sciences (Web)  (Int J Mol Sci (Web))
Volume： 19  Issue： 11  Page： 3435  Publication year： 2018 
JST Material Number： U7038A  ISSN： 1422-0067  CODEN： IJMCFK  Document type： Article
Article type： 文献レビュー  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Hepatocyte growth factor (HGF)...

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Thesaurus term： epithelium ,  stem cell ,  *HGF ,  thrombin ,  endothelial cell ,  disulfide bond ,  cellular signal transduction ,  serum ,  receptor tyrosine kinase ,  *proteinase ,  precursor(substance) ,  plasma(blood) ,  paracrine ,  robustness ,  peptidase

Author keywords (6)： hepatocyte growth factor activator ,  HGF ,  MET ,  protease ,  tissue injury ,  tissue repair

JST classification (2)： Biological function  (EB03040U) ,  Cell physiology in general  (EF02010S)

Reference (62)：

• Gohda, E.; Tsubouchi, H.; Nakayama, H.; Hirono, S.; Sakiyama, O.; Takahashi, K.; Miyazaki, H.; Hashimoto, S.; Daikuhara, Y. Purification and partial characterization of hepatocyte growth factor from plasma of a patient with fulminant hepatic failure. J. Clin. Investig. 1988, 81, 414-419.
• Weidner, K.M.; Arakaki, N.; Hartmann, G.; Vandekerckhove, J.; Weingart, S.; Rieder, H.; Fonatsch, C.; Tsubouchi, H.; Hishida, T.; Daikuhara, Y.; et al. Evidence for the identity of human scatter factor and human hepatocyte growth factor. Proc. Natl. Acad. Sci. USA 1991, 88, 7001-7005.
• Tsubouchi, H.; Gohda, E.; Strain, A.J.; Daikuhara, Y. The role of HGF-SF in animal and human hepatic physiology and pathology. EXS 1993, 65, 251-274.
• Ido, A.; Numata, M.; Kodama, M.; Tsubouchi, H. Mucosal repair and growth factors: Recombinant human hepatocyte growth factor as an innovative therapy for inflammatory bowel disease. J. Gastroenterol. 2005, 40, 925-931.
• Nakamura, T.; Sakai, K.; Nakamura, T.; Matsumoto, K. Hepatocyte growth factor twenty years on: Much more than a growth factor. J. Gastroenterol. Hepatol. 2011, 26 (Suppl. 1), 188-202.

Terms in the title (4)： 肝細胞増殖因子 ,  修復 ,  組織損傷 ,  プロテイナーゼ