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J-GLOBAL ID：201902251943005401   Reference number：19A2215704

Generation of three induced pluripotent stem cell lines from postmortem tissue derived following sudden death of a young patient with STXBP1 mutation

STXBP1突然変異の若年患者の突然死に続く死後組織からの3つの誘導多能性幹細胞株の発生【JST・京大機械翻訳】

Author (15)： Yamamoto Takuma (Division of Forensic Pathology and Science, Unit of Social Medicine, Course of Medical and Dental Sciences, Graduate School of Biomedical Sciences, Nagasaki University School of Medicine, 1-12-4 Sakamoto, Nagasaki 852-8523, Japan) ,  Otsu Makoto (Division of Stem Cell Processing/Stem Cell Bank, Center for Stem Cell Biology and Regenerative Medicine, The Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo 108-8639, Japan) ,  Okumura Takashi (Division of Stem Cell Processing/Stem Cell Bank, Center for Stem Cell Biology and Regenerative Medicine, The Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo 108-8639, Japan) ,  Horie Yumi (Division of Stem Cell Processing/Stem Cell Bank, Center for Stem Cell Biology and Regenerative Medicine, The Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo 108-8639, Japan) ,  Ueno Yasuharu (Division of Regenerative Medicine, Center for Stem Cell Biology and Regenerative Medicine, The Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo 108-8639, Japan) ,  Taniguchi Hideki (Division of Stem Cell Processing/Stem Cell Bank, Center for Stem Cell Biology and Regenerative Medicine, The Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo 108-8639, Japan) ,  Taniguchi Hideki (Division of Regenerative Medicine, Center for Stem Cell Biology and Regenerative Medicine, The Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo 108-8639, Japan) ,  Ohtaka Manami (Biotechnology Research Institute for Drug Discovery, National Institute of Advanced Industrial Science and Technology (AIST), 1-1-1 Higashi, Tsukuba, Ibaraki 305-8565, Japan) ,  Ohtaka Manami (TOKIWA-Bio Inc., G-4 Tsukuba-TCI, 2-1-6 Sengen, Tsukuba, Ibaraki 305-0047, Japan) ,  Nakanishi Mahito (Biotechnology Research Institute for Drug Discovery, National Institute of Advanced Industrial Science and Technology (AIST), 1-1-1 Higashi, Tsukuba, Ibaraki 305-8565, Japan) ,  Nakanishi Mahito (TOKIWA-Bio Inc., G-4 Tsukuba-TCI, 2-1-6 Sengen, Tsukuba, Ibaraki 305-0047, Japan) ,  Abe Yuki (Division of Forensic Pathology and Science, Unit of Social Medicine, Course of Medical and Dental Sciences, Graduate School of Biomedical Sciences, Nagasaki University School of Medicine, 1-12-4 Sakamoto, Nagasaki 852-8523, Japan) ,  Murase Takehiko (Division of Forensic Pathology and Science, Unit of Social Medicine, Course of Medical and Dental Sciences, Graduate School of Biomedical Sciences, Nagasaki University School of Medicine, 1-12-4 Sakamoto, Nagasaki 852-8523, Japan) ,  Umehara Takahiro (Division of Forensic Pathology and Science, Unit of Social Medicine, Course of Medical and Dental Sciences, Graduate School of Biomedical Sciences, Nagasaki University School of Medicine, 1-12-4 Sakamoto, Nagasaki 852-8523, Japan) ,  Ikematsu Kazuya (Division of Forensic Pathology and Science, Unit of Social Medicine, Course of Medical and Dental Sciences, Graduate School of Biomedical Sciences, Nagasaki University School of Medicine, 1-12-4 Sakamoto, Nagasaki 852-8523, Japan)
Material： Stem Cell Research (Web)  (Stem Cell Res (Web))
Volume： 39  Page： Null  Publication year： 2019 
JST Material Number： U7041A  ISSN： 1873-5061  Document type： Article
Article type： 短報  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： We established three iPSC line...

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Thesaurus term： *mutation ,  *sudden death ,  differentiation(biology) ,  brain disease ,  *human(primates) ,  fibroblast ,  child ,  clone ,  *pluripotent stem cell ,  modeling ,  genotype ,  culture(biology) ,  *versatility ,  gene ,  *death
Semi thesaurus term： 少女 , 【Automatic Indexing@JST】

JST classification (2)： Development(=generation)and differentiation  (EJ16020W) ,  Cell physiology in general  (EF02010S)

Terms in the title (7)： 突然変異 ,  若年患者 ,  突然死 ,  組織 ,  誘導 ,  多能性幹細胞 ,  株