Art

J-GLOBAL ID：201902252249485144   Reference number：19A2126017

Non-traumatic Acute Epidural Hematoma in Multiple Sclerosis Treated With Fingolimod

フィンゴリモドで治療した多発性硬化症における非外傷性急性硬膜外血腫【JST・京大機械翻訳】

Author (7)： Fukai Ryoko (Department of Neurology and Stroke Medicine, Graduate School of Medicine, Yokohama City University, Yokohama, Japan) ,  Takahashi Keita (Department of Neurology and Stroke Medicine, Graduate School of Medicine, Yokohama City University, Yokohama, Japan) ,  Abe Hiroyuki (Department of Neurosurgery, Graduate School of Medicine, Yokohama City University, Yokohama, Japan) ,  Higashiyama Yuichi (Department of Neurology and Stroke Medicine, Graduate School of Medicine, Yokohama City University, Yokohama, Japan) ,  Doi Hiroshi (Department of Neurology and Stroke Medicine, Graduate School of Medicine, Yokohama City University, Yokohama, Japan) ,  Takeuchi Hideyuki (Department of Neurology and Stroke Medicine, Graduate School of Medicine, Yokohama City University, Yokohama, Japan) ,  Tanaka Fumiaki (Department of Neurology and Stroke Medicine, Graduate School of Medicine, Yokohama City University, Yokohama, Japan)
Material： Frontiers in Neurology (Web)
Volume： 10  Page： 763  Publication year： 2019 
JST Material Number： U7085A  ISSN： 1664-2295  Document type： Article
Article type： 原著論文  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Fingolimod acts as a functiona...

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Thesaurus term： recurrence ,  *fin(machine element) ,  *extradural hemorrhage ,  case report ,  angiospasm ,  blood vessel ,  *multiple sclerosis ,  multiplex ,  remission ,  immunosuppressant ,  aliphatic carboxylic acid ,  olefin compound ,  unsaturated carboxylic acid ,  carboxylate(ester) ,  dicarboxylic acid
Semi thesaurus term： 疾患修飾 ,  *硬化症 ,  アンタゴニスト ,  *急性硬膜外血腫 , 【Automatic Indexing@JST】

Author keywords (5)： epidural hematoma ,  fingolimod ,  multiple sclerosis ,  sphingosine-1-phosphate receptor ,  vascular disruption

JST classification (1)： Nervous system diseases  (GN03000O)

Substance index (2)： Fumaric acid dimethyl ,  Fingolimod

Reference (13)：

• Pelletier D, Hafler DA. Fingolimod for multiple sclerosis. N Engl J Med. (2012) 366:339-47. doi: 10.1056/NEJMct1101691
• Camm J, Hla T, Bakshi R, Brinkmann V. Cardiac and vascular effects of fingolimod: Mechanistic basis and clinical implications. Am Heart J. (2014) 168:632-44. doi: 10.1016/j.ahj.2014.06.028
• Schwarz A, Korporal M, Hosch W, Max R, Wildemann B. Critical vasospasm during fingolimod (fty720) treatment in a patient with multiple sclerosis. Neurology. (2010) 74:2022-4. doi: 10.1212/WNL.0b013e3181e3972b
• Kappos L, Antel J, Comi G, Montalban X, O'Connor P, Polman CH, et al. Oral fingolimod (FTY720) for relapsing multiple sclerosis. N Engl J Med. (2006) 355:1124-40. doi: 10.1056/NEJMoa052643
• Xu M, Waters CL, Hu C, Wysolmerski RB, Vincent PA, Minnear FL. Sphingosine 1-phosphate rapidly increases endothelial barrier function independently of VE-cadherin but requires cell spreading and Rho kinase. Am J Physiol Cell Physiol. (2007) 293:C1309-18. doi: 10.1152/ajpcell.00014.2007

Terms in the title (5)： フィンゴリモド ,  治療 ,  多発性硬化症 ,  外傷 ,  急性硬膜外血腫