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J-GLOBAL ID：201902252292183031   Reference number：19A0021298

Polarity Acquisition in Cortical Neurons Is Driven by Synergistic Action of Sox9-Regulated Wwp1 and Wwp2 E3 Ubiquitin Ligases and Intronic miR-140

皮質ニューロンにおける極性獲得はSox9調節WWP1とWWP2 E3ユビキチンリガーゼとintronicmiR-140の相乗作用により駆動される【JST・京大機械翻訳】

Author (29)： Ambrozkiewicz Mateusz C. (Department of Molecular Neurobiology, Max Planck Institute of Experimental Medicine, Hermann-Rein-Strasse 3, 37075 Gottingen, Germany) ,  Ambrozkiewicz Mateusz C. (International Max Planck Research School for Neurosciences, Georg-August-Universitaet Gottingen, Griesebachstrasse 5, 37077 Gottingen, Germany) ,  Ambrozkiewicz Mateusz C. (Institute of Cell Biology and Neurobiology, Charite-Universitaetsmedizin Berlin, corporate member of Freie Universitaet Berlin, Humboldt-Universitaet zu Berlin, and Berlin Institute of Health, Chariteplatz 1, 10117 Berlin, Germany) ,  Schwark Manuela (Department of Molecular Neurobiology, Max Planck Institute of Experimental Medicine, Hermann-Rein-Strasse 3, 37075 Gottingen, Germany) ,  Kishimoto-Suga Mika (Department of Molecular Neurobiology, Max Planck Institute of Experimental Medicine, Hermann-Rein-Strasse 3, 37075 Gottingen, Germany) ,  Borisova Ekaterina (Institute of Cell Biology and Neurobiology, Charite-Universitaetsmedizin Berlin, corporate member of Freie Universitaet Berlin, Humboldt-Universitaet zu Berlin, and Berlin Institute of Health, Chariteplatz 1, 10117 Berlin, Germany) ,  Borisova Ekaterina (Institute of Neuroscience, Lobachevsky University of Nizhny Novgorod, pr. Gagarina 24, 603950 Nizhny Novgorod, Russian Federation) ,  Hori Kei (Department of Biochemistry and Cellular Biology, National Institute of Neuroscience, NCNP, 4-1-1 Ogawahigashi, Kodaira, Tokyo 187-8502, Japan) ,  Salazar-Lazaro Andrea (Institute of Cell Biology and Neurobiology, Charite-Universitaetsmedizin Berlin, corporate member of Freie Universitaet Berlin, Humboldt-Universitaet zu Berlin, and Berlin Institute of Health, Chariteplatz 1, 10117 Berlin, Germany) ,  Rusanova Alexandra (Institute of Cell Biology and Neurobiology, Charite-Universitaetsmedizin Berlin, corporate member of Freie Universitaet Berlin, Humboldt-Universitaet zu Berlin, and Berlin Institute of Health, Chariteplatz 1, 10117 Berlin, Germany) ,  Rusanova Alexandra (Institute of Neuroscience, Lobachevsky University of Nizhny Novgorod, pr. Gagarina 24, 603950 Nizhny Novgorod, Russian Federation) ,  Altas Bekir (Department of Molecular Neurobiology, Max Planck Institute of Experimental Medicine, Hermann-Rein-Strasse 3, 37075 Gottingen, Germany) ,  Altas Bekir (International Max Planck Research School for Neurosciences, Georg-August-Universitaet Gottingen, Griesebachstrasse 5, 37077 Gottingen, Germany) ,  Piepkorn Lars (Proteomics Group, Max Planck Institute of Experimental Medicine, Hermann-Rein-Strasse 3, 37075 Gottingen, Germany) ,  Bessa Paraskevi (Institute of Cell Biology and Neurobiology, Charite-Universitaetsmedizin Berlin, corporate member of Freie Universitaet Berlin, Humboldt-Universitaet zu Berlin, and Berlin Institute of Health, Chariteplatz 1, 10117 Berlin, Germany) ,  Schaub Theres (Institute of Cell Biology and Neurobiology, Charite-Universitaetsmedizin Berlin, corporate member of Freie Universitaet Berlin, Humboldt-Universitaet zu Berlin, and Berlin Institute of Health, Chariteplatz 1, 10117 Berlin, Germany) ,  Zhang Xin (Molecular Oncology, Medical University of Gottingen, Justus-von-Liebig-Weg 11, 37077 Gottingen, Germany) ,  Rabe Tamara (Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, 37077 Gottingen, Germany) ,  Ripamonti Silvia (Department of Molecular Neurobiology, Max Planck Institute of Experimental Medicine, Hermann-Rein-Strasse 3, 37075 Gottingen, Germany) ,  Rosario Marta (Institute of Cell Biology and Neurobiology, Charite-Universitaetsmedizin Berlin, corporate member of Freie Universitaet Berlin, Humboldt-Universitaet zu Berlin, and Berlin Institute of Health, Chariteplatz 1, 10117 Berlin, Germany) ,  Akiyama Haruhiko (Department of Orthopaedic Surgery, Gifu University, 1-1 Yanagito, Gifu 501-1193, Japan) ,  Jahn Olaf (Proteomics Group, Max Planck Institute of Experimental Medicine, Hermann-Rein-Strasse 3, 37075 Gottingen, Germany) ,  Kobayashi Tatsuya (Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA) ,  Hoshino Mikio (Department of Biochemistry and Cellular Biology, National Institute of Neuroscience, NCNP, 4-1-1 Ogawahigashi, Kodaira, Tokyo 187-8502, Japan) ,  Tarabykin Victor (Institute of Cell Biology and Neurobiology, Charite-Universitaetsmedizin Berlin, corporate member of Freie Universitaet Berlin, Humboldt-Universitaet zu Berlin, and Berlin Institute of Health, Chariteplatz 1, 10117 Berlin, Germany) ,  Tarabykin Victor (Institute of Neuroscience, Lobachevsky University of Nizhny Novgorod, pr. Gagarina 24, 603950 Nizhny Novgorod, Russian Federation) ,  Kawabe Hiroshi (Department of Molecular Neurobiology, Max Planck Institute of Experimental Medicine, Hermann-Rein-Strasse 3, 37075 Gottingen, Germany) ,  Kawabe Hiroshi (Division of Pathogenetic Signaling, Department of Biochemistry and Molecular Biology, Kobe University Graduate School of Medicine, 1-5-6 Minatojima-minamimachi, Chuo-ku, Kobe 650-0047, Japan) ,  Kawabe Hiroshi (Department of Gerontology, Laboratory of Molecular Life Science, Institute of Biomedical Research and Innovation, Foundation for Biomedical Research and Innovation at Kobe, 2-2 Minatojima-Minamimachi Chuo-ku, Kobe 650-0047, Japan)
Material： Neuron
Volume： 100  Issue： 5  Page： 1097-1115.e15  Publication year： 2018 
JST Material Number： T0649A  ISSN： 0896-6273  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： The establishment of axon-dend...

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Thesaurus term： *ubiquitin ,  *cortex(animal tissue) ,  *polarity ,  transcription factor ,  laminar flow ,  axon ,  differentiation(biology) ,  mRNA ,  *neuron ,  dendrite(neuron) ,  phenotype ,  Mammalia
Semi thesaurus term： *miR-140 ,  *SOX9転写因子 ,  *皮質ニューロン , 【Automatic Indexing@JST】

Author keywords (7)： neuronal development ,  axon formation ,  neuronal migration ,  neuronal differentiation ,  ubiquitin ,  intronic microRNA ,  host gene

JST classification (1)： Central nervous system  (EJ12030F)

Terms in the title (7)： 皮質ニューロン ,  極性 ,  獲得 ,  Sox9 ,  調節 ,  E3ユビキチンリガーゼ ,  相乗作用