Art

J-GLOBAL ID：201902252558790621   Reference number：19A2516080

Pharmacokinetics of thiotepa in high-dose regimens for autologous hematopoietic stem cell transplant in Japanese patients with pediatric tumors or adult lymphoma

小児腫瘍または成人リンパ腫の日本人患者における自家造血幹細胞移植のための高用量レジメンにおけるチオテパの薬物動態【JST・京大機械翻訳】

Author (11)： Kondo Eisei (Department of Hematology and Oncology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan) ,  Kondo Eisei (Department of Hematology, Kawasaki Medical School, Kurashiki, Japan) ,  Ikeda Takashi (Division of Hematology and Stem Cell Transplantation, Shizuoka Cancer Center, Shizuoka, Japan) ,  Goto Hiroaki (Hematology/Oncology and Regenerative Medicine, Kanagawa Children’s Medical Center, Yokohama, Japan) ,  Nishikori Momoko (Department of Hematology and Oncology, Graduate School of Medicine, Kyoto University, Kyoto, Japan) ,  Maeda Naoko (Department of Pediatrics, National Hospital Organization Nagoya Medical Center, Nagoya, Japan) ,  Matsumoto Kimikazu (Children’s Cancer Center, National Center for Child Health and Development, Tokyo, Japan) ,  Kitagawa Hideo (Sumitomo Dainippon Pharma Co., Ltd., Osaka, Japan) ,  Noda Naoto (Sumitomo Dainippon Pharma Co., Ltd., Osaka, Japan) ,  Sugimoto Saori (Sumitomo Dainippon Pharma Co., Ltd., Osaka, Japan) ,  Hara Junichi (Department of Pediatric Hematology/Oncology, Children’s Medical Center, Osaka City General Hospital, Osaka, Japan)
Material： Cancer Chemotherapy and Pharmacology
Volume： 84  Issue： 4  Page： 849-860  Publication year： 2019 
JST Material Number： W4134A  ISSN： 1432-0843  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Abstract/Point： Thiotepa is used in high-dose ...

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Thesaurus term： *pharmacokinetics ,  effectiveness ,  clearance ,  *lymphoma ,  *child ,  *adult(person) ,  brain tumor ,  *human(primates) ,  survival ratio ,  solid tumor ,  safety ,  *hematopoietic stem cell transplantation ,  nitrogen heterocyclic compound
Semi thesaurus term： 有害事象 ,  *レジメン ,  *日本人 , 【Automatic Indexing@JST】

Author keywords (4)： HSCT ,  Pharmacokinetics ,  TEPA ,  Thiotepa

JST classification (5)： Clinical biopharmacy  (GY01022L) ,  Treatment for hematologic diseases in general  (GK05010E) ,  Clinical oncology in general  (GE03010Y) ,  Clinical application of antitumor(=antineoplastic)drugs  (GW16020L) ,  Blood cell tumors(=neoplasms)  (GK04000M)

Substance index (1)： Thiotepa

Terms in the title (10)： 小児腫瘍 ,  成人 ,  リンパ腫 ,  日本人 ,  患者 ,  自家造血幹細胞移植 ,  高用量 ,  レジメン ,  チオテパ ,  薬物動態