Art

J-GLOBAL ID：201902253664719980   Reference number：19A2233569

Di-(2-ethylhexyl) phthalate suppresses IL-12p40 production by GM-CSF-dependent macrophages via the PPARα/TNFAIP3/TRAF6 axis after lipopolysaccharide stimulation

ジ-(2-エチルヘキシル)フタラートはリポ多糖類刺激後のPPARα/TNFAIP3/TRAF6軸を介してGM-CSF依存性マクロファージによるIL-12p40産生を抑制する【JST・京大機械翻訳】

Author (9)： Yamaguchi R (Department of Public Health, Faculty of Life Sciences, Kumamoto University School of Medicine, Kumamoto, Japan) ,  Yamaguchi R (Graduate School of Medical Science, Kumamoto Health Science University, Kumamoto, Japan) ,  Sakamoto A (Graduate School of Medical Science, Kumamoto Health Science University, Kumamoto, Japan) ,  Yamamoto T (Graduate School of Medical Science, Kumamoto Health Science University, Kumamoto, Japan) ,  Narahara S (Graduate School of Medical Science, Kumamoto Health Science University, Kumamoto, Japan) ,  Sugiuchi H (Graduate School of Medical Science, Kumamoto Health Science University, Kumamoto, Japan) ,  Hisada A (Department of Public Health, Faculty of Life Sciences, Kumamoto University School of Medicine, Kumamoto, Japan) ,  Katoh T (Department of Public Health, Faculty of Life Sciences, Kumamoto University School of Medicine, Kumamoto, Japan) ,  Yamaguchi Y (Graduate School of Medical Science, Kumamoto Health Science University, Kumamoto, Japan)
Material： Human & Experimental Toxicology  (Hum Exp Toxicol)
Volume： 37  Issue： 6  Page： 596-607  Publication year： 2018 
JST Material Number： H0825A  ISSN： 0960-3271  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： Activation of peroxisome proli...

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Thesaurus term： *PPAR alpha ,  Gene Silencing ,  interleukin ,  siRNA ,  culture (biology) ,  Up-Regulation ,  *lipopolysaccharide ,  *macrophage ,  anti-inflammatory action ,  granulocyte (leucocyte) ,  TNF alpha ,  Transfection ,  A20 protein ,  *interleukin12p40 ,  *TNF Receptor-Associated Factor 6

Author keywords (6)： Di-(2-ethylhexyl) phthalate ,  granulocyte-macrophage colony-stimulating factor ,  macrophage ,  peroxisome proliferator-activated receptor α ,  tumor necrosis factor α-induced protein 3 ,  tumor necrosis factor receptor-associated factor 6

JST classification (1)： Immunological reaction in general  (ED03010T)

Terms in the title (11)： ヘキシル ,  フタラート ,  リポ多糖類 ,  刺激 ,  PPARα ,  TNFAIP3 ,  TRAF6 ,  GM-CSF ,  依存性 ,  マクロファージ ,  IL-12p40