Art

J-GLOBAL ID：201902253946240104   Reference number：19A0165547

Decitabine exerted synergistic effects with oxaliplatin in colorectal cancer cells with intrinsic resistance to decitabine

デシタビンに対する固有耐性を有する結腸直腸癌細胞におけるオキサリプラチンとの相乗効果を発揮するデシタビン【JST・京大機械翻訳】

Author (5)： Hosokawa Mika (Department of Pharmaceutics, Kobe Pharmaceutical University, 4-19-1 Motoyamakita-machi, Higashinada-ku, Kobe 658-8558, Japan) ,  Tanaka Shota (Department of Pharmaceutics, Kobe Pharmaceutical University, 4-19-1 Motoyamakita-machi, Higashinada-ku, Kobe 658-8558, Japan) ,  Ueda Kumiko (Department of Pharmaceutics, Kobe Pharmaceutical University, 4-19-1 Motoyamakita-machi, Higashinada-ku, Kobe 658-8558, Japan) ,  Iwakawa Seigo (Department of Pharmaceutics, Kobe Pharmaceutical University, 4-19-1 Motoyamakita-machi, Higashinada-ku, Kobe 658-8558, Japan) ,  Ogawara Ken-ichi (Department of Pharmaceutics, Kobe Pharmaceutical University, 4-19-1 Motoyamakita-machi, Higashinada-ku, Kobe 658-8558, Japan)
Material： Biochemical and Biophysical Research Communications  (BBRC)
Volume： 509  Issue： 1  Page： 249-254  Publication year： 2019 
JST Material Number： B0118A  ISSN： 0006-291X  Document type： Article
Article type： 短報  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Epigenetic modifiers such as d...

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Thesaurus term： sensitivity ,  combination therapy ,  DNA lesion ,  *potentiation ,  DNA ,  scavenger ,  antitumor drug ,  cytotoxicity ,  human ,  mRNA expression ,  gamma H2AX ,  HT 29 Cells
Semi thesaurus term： 阻害剤 ,  *オキサリプラチン ,  *結腸直腸癌 , 【Automatic Indexing@JST】

Author keywords (6)： Decitabine ,  Oxaliplatin ,  Combination ,  Synergistic effect ,  Reactive oxygen species ,  Colorectal cancer

JST classification (2)： Basic research of antitumor(=antineoplastic)drugs  (GW16010A) ,  Basic research of enzyme preparations and enzyme inhibitor preparations  (GW21010W)

Terms in the title (7)： デシタビン ,  固有 ,  耐性 ,  結腸直腸 ,  癌細胞 ,  オキサリプラチン ,  相乗効果