Art

J-GLOBAL ID：201902254717594487   Reference number：19A1818670

Protein Glycosylation and Tumor Microenvironment Alterations Driving Cancer Hallmarks

癌の特徴を駆動する蛋白質グリコシル化と腫瘍微小環境変化【JST・京大機械翻訳】

Author (12)： Peixoto Andreia (Experimental Pathology and Therapeutics Group, Portuguese Institute of Oncology, Porto, Portugal) ,  Peixoto Andreia (Institute of Biomedical Sciences Abel Salazar, University of Porto, Porto, Portugal) ,  Peixoto Andreia (Tumour and Microenvironment Interactions Group, INEB-Institute for Biomedical Engineering, Porto, Portugal) ,  Peixoto Andreia (Instituto de Investigacao e Inovacao em Saude, Universidade do Porto, Porto, Portugal) ,  Relvas-Santos Marta (Experimental Pathology and Therapeutics Group, Portuguese Institute of Oncology, Porto, Portugal) ,  Azevedo Rita (Experimental Pathology and Therapeutics Group, Portuguese Institute of Oncology, Porto, Portugal) ,  Azevedo Rita (Institute of Biomedical Sciences Abel Salazar, University of Porto, Porto, Portugal) ,  Santos Lucio Lara (Experimental Pathology and Therapeutics Group, Portuguese Institute of Oncology, Porto, Portugal) ,  Santos Lucio Lara (Department of Surgical Oncology, Portuguese Institute of Oncology, Porto, Portugal) ,  Ferreira Jose Alexandre (Experimental Pathology and Therapeutics Group, Portuguese Institute of Oncology, Porto, Portugal) ,  Ferreira Jose Alexandre (Institute of Biomedical Sciences Abel Salazar, University of Porto, Porto, Portugal) ,  Ferreira Jose Alexandre (Porto Comprehensive Cancer Center, Porto, Portugal)
Material： Frontiers in Oncology (Web)
Volume： 9  Page： 380  Publication year： 2019 
JST Material Number： U7089A  ISSN： 2234-943X  Document type： Article
Article type： 文献レビュー  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Decades of research have discl...

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Thesaurus term： *glycosylation ,  biosynthesis ,  glycoconjugate ,  carcinogenesis ,  crosstalk(interaction) ,  *protein ,  interstitial tissue ,  epitope ,  phenotype
Semi thesaurus term： 患者介護 ,  グリカン ,  *微小環境 ,  グリコプロテオーム ,  *腫瘍内微小環境 , 【Automatic Indexing@JST】

Author keywords (5)： cancer ,  microenvironment ,  glycans ,  protein glycosylation ,  cancer hallmarks

JST classification (2)： Cell physiology in general  (EF02010S) ,  Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N)

Reference (303)：

• Shental-Bechor D, Levy Y. Effect of glycosylation on protein folding: a close look at thermodynamic stabilization. Proc Natl Acad Sci USA. (2008) 105:8256-61. doi: 10.1073/pnas.0801340105
• Vagin O, Kraut JA, Sachs G. Role of N-glycosylation in trafficking of apical membrane proteins in epithelia. Am J Physiol Renal Physiol. (2009) 296:F459-69. doi: 10.1152/ajprenal.90340.2008
• Ono M, Hakomori S. Glycosylation defining cancer cell motility and invasiveness. Glycoconj J. (2004) 20:71-8. doi: 10.1023/B:GLYC.0000018019.22070.7d
• Ohtsubo K, Marth JD. Glycosylation in cellular mechanisms of health and disease. Cell. (2006) 126:855-67. doi: 10.1016/j.cell.2006.08.019
• Stowell SR, Ju T, Cummings RD. Protein glycosylation in cancer. Annu Rev Pathol. (2015) 10:473-510. doi: 10.1146/annurev-pathol-012414-040438

Terms in the title (4)： 癌 ,  蛋白質 ,  グリコシル化 ,  腫瘍微小環境