Art

J-GLOBAL ID：201902255454765496   Reference number：19A2301619

Identification of Blood-Brain Barrier-Permeable Proteins Derived from a Peripheral Organ: In Vivo and in Vitro Evidence of Blood-to-Brain Transport of Creatine Kinase

末梢器官由来の血液脳関門透過性蛋白質の同定:クレアチンキナーゼの血液から脳への輸送のin vivoおよびin vitroでの証拠【JST・京大機械翻訳】

Author (6)： Sato Kazuki (Division of Membrane Transport and Drug Targeting, Graduate School of Pharmaceutical Sciences, Tohoku University, Japan) ,  Tachikawa Masanori (Division of Membrane Transport and Drug Targeting, Graduate School of Pharmaceutical Sciences, Tohoku University, Japan) ,  Watanabe Michitoshi (Division of Membrane Transport and Drug Targeting, Graduate School of Pharmaceutical Sciences, Tohoku University, Japan) ,  Miyauchi Eisuke (Division of Membrane Transport and Drug Targeting, Graduate School of Pharmaceutical Sciences, Tohoku University, Japan) ,  Uchida Yasuo (Division of Membrane Transport and Drug Targeting, Graduate School of Pharmaceutical Sciences, Tohoku University, Japan) ,  Terasaki Tetsuya (Division of Membrane Transport and Drug Targeting, Graduate School of Pharmaceutical Sciences, Tohoku University, Japan)
Material： Molecular Pharmaceutics
Volume： 16  Issue： 1  Page： 247-257  Publication year： 2019 
JST Material Number： W3686A  ISSN： 1543-8384  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： Certain proteins, such as infl...

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Thesaurus term： dysfunction ,  *blood-brain barrier ,  viscus ,  *in vitro experiment ,  *protein ,  endocytosis ,  cytosol ,  mouse(animal) ,  human(primates) ,  *creatine kinase ,  biotinylation ,  pathogenesis
Semi thesaurus term： 阻害剤 ,  カベオリン ,  *器官 , 【Automatic Indexing@JST】

Author keywords (5)： blood-brain barrier ,  blood-brain barrier-permeable protein ,  creatine kinase ,  comprehensive quantitative proteomics ,  peripheral-to-CNS communication

JST classification (2)： Basic biopharmacy  (GY01021U) ,  Basic research of diagnostic drugs  (GW20010P)

Terms in the title (9)： 器官 ,  血液脳関門透過性 ,  蛋白質 ,  同定 ,  クレアチンキナーゼ ,  血液 ,  脳 ,  輸送 ,  証拠