Art

J-GLOBAL ID：201902256799943060   Reference number：19A1706765

Prediction Accuracy of Mechanism-Based Oral Absorption Model for Dogs

イヌのためのメカニズムに基づく経口吸収モデルの予測精度【JST・京大機械翻訳】

Author (10)： Akiyama Yoshiyuki (Drug Metabolism & Pharmacokinetics Research Laboratories, Central Pharmaceutical Research Institute, Japan Tobacco Inc, 1-1 Murasaki-cho, Takatsuki, Osaka 569-1125, Japan) ,  Kimoto Takahiro (Product Development Laboratories, Central Pharmaceutical Research Institute, Japan Tobacco Inc., 1-1 Murasaki-cho, Takatsuki, Osaka 569-1125, Japan) ,  Mukumoto Hanae (Product Development Laboratories, Central Pharmaceutical Research Institute, Japan Tobacco Inc., 1-1 Murasaki-cho, Takatsuki, Osaka 569-1125, Japan) ,  Miyake Shuji (Product Development Laboratories, Central Pharmaceutical Research Institute, Japan Tobacco Inc., 1-1 Murasaki-cho, Takatsuki, Osaka 569-1125, Japan) ,  Ito Soichiro (Drug Metabolism & Pharmacokinetics Research Laboratories, Central Pharmaceutical Research Institute, Japan Tobacco Inc, 1-1 Murasaki-cho, Takatsuki, Osaka 569-1125, Japan) ,  Taniguchi Toshio (Drug Metabolism & Pharmacokinetics Research Laboratories, Central Pharmaceutical Research Institute, Japan Tobacco Inc, 1-1 Murasaki-cho, Takatsuki, Osaka 569-1125, Japan) ,  Nomura Yukihiro (Drug Metabolism & Pharmacokinetics Research Laboratories, Central Pharmaceutical Research Institute, Japan Tobacco Inc, 1-1 Murasaki-cho, Takatsuki, Osaka 569-1125, Japan) ,  Matsumura Naoya (Early Stage Oral Formulation Research & Development, Pharmaceutical Research & Development, Ono Pharmaceutical Co., Ltd., 3-1-1 Sakurai, Shimamoto-cho, Mishima-gun, Osaka 618-8585, Japan) ,  Fujita Takuya (Laboratory of Molecular Pharmacokinetics, College of Pharmaceutical Sciences, Ritsumeikan University, 1-1-1 Noji-higashi, Kusatsu, Shiga 525-8577, Japan) ,  Sugano Kiyohiko (Molecular Pharmaceutics Lab., College of Pharmaceutical Sciences, Ritsumeikan University, 1-1-1 Noji-higashi, Kusatsu, Shiga 525-8577, Japan)
Material： Journal of Pharmaceutical Sciences  (J Pharm Sci)
Volume： 108  Issue： 8  Page： 2728-2736  Publication year： 2019 
JST Material Number： C0260B  ISSN： 0022-3549  CODEN： JPMSAE  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： The purpose of the present stu...

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Thesaurus term： *model ,  pH ,  small intestine ,  literature search ,  *oral absorption ,  modeling ,  Physico-chemical property ,  neutral ,  *prediction accuracy

Author keywords (5)： oral absorption ,  mechanistic modeling ,  intestinal absorption ,  pH ,  physicochemical properties

JST classification (1)： Metabolism and nutrition of lipids  (EJ02034Q)

Terms in the title (5)： イヌ ,  メカニズム ,  経口吸収 ,  モデル ,  予測精度