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J-GLOBAL ID:201902257260579099   Reference number:19A0221678

Estimation of the Area under the Concentration-time Curve for Mycophenolic Acid Using Population Pharmacokinetics in Heart Transplantation Recipients

心臓移植後患者における母集団薬物動態解析を用いたミコフェノール酸AUC0-12h推定法の検討
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Volume: 45  Issue:Page: 1-10  Publication year: Jan. 10, 2019 
JST Material Number: Y0888A  ISSN: 1346-342X  CODEN: IYRAA3  Document type: Article
Article type: 原著論文  Country of issue: Japan (JPN)  Language: JAPANESE (JA)
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Clinical biopharmacy 
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Reference (19):
  • 1)European Mycophenolate Mofetil Cooperative Study Group, Placebo-controlled study of mycophenolate mofetil combined with cyclosporin and corticosteroids for prevention of acute rejection, Lancet, 1995, 345, 1321-1325.
  • 2)Kobashigawa J, Miller L, Renlund D, Mentzer R, Alderman E, Bourge R, Costanzo M, Eisen H, Dureau G, Ratkovec R, Hummel M, Ipe D, Johnson J, Keogh A, Mamelok R, Mancini D, Smart F, Valantine H, A randomized active-controlled trial of mycophenolate mofetil in heart transplant recipients, Transplantation, 1998, 66, 507-515.
  • 3)Kuypers DR, Claes K, Evenepoel P, Maes B, Vanrenterghem Y, Clinical efficacy and toxicity profile of tacrolimus and mycophenolic acid in relation to combined long-term pharmacokinetics in de novo renal allograft recipients, Clin Pharmacol Ther, 2004, 75, 434-447.
  • 4)Kuypers DR, de Jonge H, Naesens M, de Loor H, Halewijck E, Dekens M, Vanrenterghem Y, Current target ranges of mycophenolic acid exposure and drug-related adverse events: a 5-year, open-label, prospective, clinical follow-up study in renal allograft recipients, Clin Ther, 2008, 30, 673-683.
  • 5)Pillans PI, Rigby RJ, Kubler P, Willis C, Salm P, Tett SE, Taylor PJ, A retrospective analysis of mycophenolic acid and cyclosporin concentrations with acute rejection in renal transplant recipients, Clin Biochem, 2001, 34, 77-81.
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