Art

J-GLOBAL ID：201902257285178369   Reference number：19A2215435

Sitagliptin inhibits vascular inflammation via the SIRT6-dependent signaling pathway

シタグリプチンはSIRT6依存性シグナル伝達経路を介して血管炎症を阻害する【JST・京大機械翻訳】

Author (12)： He Yanhao (Department of Pharmacology, Xi’an Jiaotong University, Health Science Center, Xi’an, Shaanxi 710061, China) ,  Yang Guangde (School of Pharmacy, Xi’an Jiaotong University, Health Science Center, Xi’an, Shaanxi 710061, China) ,  Yao Feng (School of Pharmacy, Xi’an Jiaotong University, Health Science Center, Xi’an, Shaanxi 710061, China) ,  Xian Yushan (Department of Pharmacology, Xi’an Jiaotong University, Health Science Center, Xi’an, Shaanxi 710061, China) ,  Wang Guan (School of Pharmacy, Xi’an Jiaotong University, Health Science Center, Xi’an, Shaanxi 710061, China) ,  Chen Lifang (Laboratory Animal Center, Xi’an Jiaotong University, Health Science Center, Xi’an, Shaanxi 710061, China) ,  Lv Xiaohan (Department of Pharmacology, Xi’an Jiaotong University, Health Science Center, Xi’an, Shaanxi 710061, China) ,  Gao Hongqian (Department of Pharmacology, Xi’an Jiaotong University, Health Science Center, Xi’an, Shaanxi 710061, China) ,  Zheng Zihan (Department of Pharmacology, Xi’an Jiaotong University, Health Science Center, Xi’an, Shaanxi 710061, China) ,  Sun Lijing (Department of Pharmacy, Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi 710004, China) ,  Wang Weirong (Laboratory Animal Center, Xi’an Jiaotong University, Health Science Center, Xi’an, Shaanxi 710061, China) ,  Lin Rong (Department of Pharmacology, Xi’an Jiaotong University, Health Science Center, Xi’an, Shaanxi 710061, China)
Material： International Immunopharmacology  (Int Immunopharmacol)
Volume： 75  Page： Null  Publication year： 2019 
JST Material Number： T0026B  ISSN： 1567-5769  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Sitagliptin has recently been ...

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Thesaurus term： endothelial cell ,  interleukin 1 ,  endothelium ,  *vasculitis ,  histone deacetylase ,  intraperitoneal administration ,  TNF alpha ,  up-regulation ,  *inflammation ,  animal
Semi thesaurus term： 遺伝子ノックダウン法 ,  インターロイキン1β ,  炎症反応 ,  *伝達経路 , 【Automatic Indexing@JST】

Author keywords (4)： Sitagliptin ,  SIRT6 ,  Inflammation ,  ROS

JST classification (5)： Basic research of immunotherapeutic agents and blood preparations  (GW22010D) ,  Cell physiology in general  (EF02010S) ,  Receptors on cell membrane  (EF04030C) ,  Cytokines  (EB08090G) ,  Biological function  (EB06020T)

Substance index (1)： Sitagliptin

Terms in the title (6)： シタグリプチン ,  Sirt6 ,  依存性 ,  シグナル伝達経路 ,  血管炎症 ,  阻害