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J-GLOBAL ID：201902257673133109   Reference number：19A1522410

5-FU系抗癌剤薬物代謝に関わるピリミジン分解経路異常症のスクリーニング法の確立

Author (3)： NAKAJIMA YOKO (藤田医大 医 小児科学) ,  MAEDA YASUHIRO (藤田医大 研究支援推進本部 共同利用研究推進設備サポートセ) ,  ITO TETSUYA (藤田医大 医 小児科学)
Material： 臨床薬理の進歩  (Recent Advances in Clinical Pharmacology)
Issue： 40  Page： 131-139  Publication year： Jun. 25, 2019 
JST Material Number： Y0720A  ISSN： 0914-4366  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： JAPANESE (JA)

Thesaurus term： *antineoplastic antimetabolite ,...
Semi thesaurus term： UPLC-MS/MS analysis ,...

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JST classification (1)： Clinical biopharmacy  (GY01022L)

Substance index (1)： Fluorouracil

Reference (14)：

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• Tuchman M, Stoeckeler JS, Kiang DT, O'Dea RF, Ramnaraine ML, Mirkin BL. Familial pyrimidinemia and pyrimidinuria associated with severe fluorouracil toxicity. N Engl J Med 1985; 313(4): 245-9.

Terms in the title (6)： 5-FU ,  抗癌剤 ,  薬物代謝 ,  ピリミジン ,  分解経路 ,  スクリーニング法