Art

J-GLOBAL ID：201902257752388122   Reference number：19A2691334

Short TRPM2 prevents the targeting of full-length TRPM2 to the surface transmembrane by hijacking to ER associated degradation

短いTRPM2はER関連分解への推進による完全長TRPM2の表面膜貫通への標的化を妨げる【JST・京大機械翻訳】

Author (5)： Yamamoto Shinichiro (Division of Pharmacology, Faculty of Pharmaceutical Sciences, Teikyo Heisei University, Tokyo, 164-8530, Japan) ,  Ishii Takahiro (Division of Pharmacology, Faculty of Pharmaceutical Sciences, Teikyo Heisei University, Tokyo, 164-8530, Japan) ,  Mikami Ryota (Division of Pharmacology, Faculty of Pharmaceutical Sciences, Teikyo Heisei University, Tokyo, 164-8530, Japan) ,  Numata Tomohiro (Department of Physiology, Graduate School of Medical Science, Fukuoka University, Fukuoka, 814-0180, Japan) ,  Shimizu Shunichi (Division of Pharmacology, Faculty of Pharmaceutical Sciences, Teikyo Heisei University, Tokyo, 164-8530, Japan)
Material： Biochemical and Biophysical Research Communications  (BBRC)
Volume： 520  Issue： 3  Page： 520-525  Publication year： 2019 
JST Material Number： B0118A  ISSN： 0006-291X  Document type： Article
Article type： 短報  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Membrane proteins are targeted...

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Thesaurus term： interaction ,  substrate (biochemistry) ,  sensitivity ,  *targeting ,  receptor ,  Membrane Proteins ,  Ubiquitination ,  proteasome ,  channel ,  oxidative stress ,  Endoplasmic Reticulum ,  co-expression ,  ER associated degradation ,  *TRPM2
Semi thesaurus term： 阻害剤 , 【Automatic Indexing@JST】

Author keywords (4)： TRPM2 ,  Splicing variant ,  Protein quality control systems ,  ERAD

JST classification (1)： Cell components in general  (EF03010Z)

Terms in the title (5)： TRPM2 ,  Er ,  分解 ,  推進 ,  標的化