Art

J-GLOBAL ID：201902258505791125   Reference number：19A1549518

Protein S is Protective in Acute Lung Injury by Inhibiting Cell Apoptosis

蛋白質Sは細胞アポトーシスを阻害することにより急性肺損傷において保護する【JST・京大機械翻訳】

Author (15)： Tonto Prince Baffour (Department of Immunology, Mie University, Graduate School of Medicine Mie, Edobashi 2-174, Tsu, Mie 514-8507, Japan) ,  Yasuma Taro (Department of Immunology, Mie University, Graduate School of Medicine Mie, Edobashi 2-174, Tsu, Mie 514-8507, Japan) ,  Yasuma Taro (Department of Diabetes and Endocrinology, Mie University, Graduate School of Medicine Mie, Edobashi 2-174, Tsu, Mie 514-8507, Japan) ,  Kobayashi Tetsu (Department of Pulmonary and Critical Care Medicine, Mie University, Graduate School of Medicine Mie, Edobashi 2-174, Tsu, Mie 514-8507, Japan) ,  D'Alessandro-Gabazza Corina N. (Department of Immunology, Mie University, Graduate School of Medicine Mie, Edobashi 2-174, Tsu, Mie 514-8507, Japan) ,  Toda Masaaki (Department of Immunology, Mie University, Graduate School of Medicine Mie, Edobashi 2-174, Tsu, Mie 514-8507, Japan) ,  Saiki Haruko (Department of Pulmonary and Critical Care Medicine, Mie University, Graduate School of Medicine Mie, Edobashi 2-174, Tsu, Mie 514-8507, Japan) ,  Fujimoto Hajime (Department of Pulmonary and Critical Care Medicine, Mie University, Graduate School of Medicine Mie, Edobashi 2-174, Tsu, Mie 514-8507, Japan) ,  Asayama Kentaro (Department of Pulmonary and Critical Care Medicine, Mie University, Graduate School of Medicine Mie, Edobashi 2-174, Tsu, Mie 514-8507, Japan) ,  Fujiwara Kentaro (Department of Pulmonary and Critical Care Medicine, Mie University, Graduate School of Medicine Mie, Edobashi 2-174, Tsu, Mie 514-8507, Japan) ,  Nishihama Kota (Department of Diabetes and Endocrinology, Mie University, Graduate School of Medicine Mie, Edobashi 2-174, Tsu, Mie 514-8507, Japan) ,  Okano Tomohito (Department of Pulmonary and Critical Care Medicine, Mie University, Graduate School of Medicine Mie, Edobashi 2-174, Tsu, Mie 514-8507, Japan) ,  Takeshita Atsuro (Department of Immunology, Mie University, Graduate School of Medicine Mie, Edobashi 2-174, Tsu, Mie 514-8507, Japan) ,  Takeshita Atsuro (Department of Diabetes and Endocrinology, Mie University, Graduate School of Medicine Mie, Edobashi 2-174, Tsu, Mie 514-8507, Japan) ,  Gabazza Esteban C. (Department of Immunology, Mie University, Graduate School of Medicine Mie, Edobashi 2-174, Tsu, Mie 514-8507, Japan)
Material： International Journal of Molecular Sciences (Web)  (Int J Mol Sci (Web))
Volume： 20  Issue： 5  Page： 1082  Publication year： 2019 
JST Material Number： U7038A  ISSN： 1422-0067  CODEN： IJMCFK  Document type： Article
Article type： 原著論文  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Acute lung injury is a fatal d...

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Thesaurus term： phosphorylation ,  edema ,  anti-inflammatory action ,  myeloperoxidase ,  transgenic mouse ,  human ,  inflammatory cytokine ,  pulmonary alveolus ,  Western blotting ,  lipopolysaccharide ,  *Apoptosis ,  *Proteins ,  wild-type mouse ,  anti-apoptotic effect ,  peroxidase ,  bioassay
Semi thesaurus term： *急性肺損傷 , 【Automatic Indexing@JST】

Author keywords (6)： acute lung injury ,  protein S ,  apoptosis ,  signal pathway ,  Erk1/2 ,  lipopolysaccharide

JST classification (3)： Cell physiology in general  (EF02010S) ,  Immunological reaction in general  (ED03010T) ,  Basic research of antitumor(=antineoplastic)drugs  (GW16010A)

Reference (29)：

• Fan, E.; Brodie, D.; Slutsky, A.S. Acute Respiratory Distress Syndrome: Advances in Diagnosis and Treatment. JAMA 2018, 319, 698-710.
• Umbrello, M.; Formenti, P.; Bolgiaghi, L.; Chiumello, D. Current Concepts of ARDS: A Narrative Review. Int. J. Mol. Sci. 2016, 18, 64.
• Laffey, J.G.; Madotto, F.; Bellani, G.; Pham, T.; Fan, E.; Brochard, L.; Amin, P.; Arabi, Y.; Bajwa, E.K.; Bruhn, A.; et al. Geo-economic variations in epidemiology, patterns of care, and outcomes in patients with acute respiratory distress syndrome: Insights from the LUNG SAFE prospective cohort study. Lancet Respir. Med. 2017, 5, 627-638.
• Mutlu, G.M.; Budinger, G.R. Incidence and outcomes of acute lung injury. N. Engl. J. Med. 2006, 354, 416-417; author reply 416-417.
• Bellani, G.; Laffey, J.G.; Pham, T.; Fan, E.; Brochard, L.; Esteban, A.; Gattinoni, L.; van Haren, F.; Larsson, A.; McAuley, D.F.; et al. Epidemiology, Patterns of Care, and Mortality for Patients With Acute Respiratory Distress Syndrome in Intensive Care Units in 50 Countries. JAMA 2016, 315, 788-800.

Terms in the title (4)： 蛋白質S ,  細胞アポトーシス ,  阻害 ,  急性肺損傷