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J-GLOBAL ID：201902259664179353   Reference number：19A0955804

Aggregatibacter actinomycetemcomitans induces detachment and death of human gingival epithelial cells and fibroblasts via elastase release following leukotoxin-dependent neutrophil lysis

Aggregatibacter actinomycetemcomitansはロイコトキシン依存性好中球溶解後のエラスターゼ放出を介してヒト歯肉上皮細胞および線維芽細胞の剥離と死を誘導する

Author (19)： Hiyoshi Takumi (Division of Microbiology and Infectious Diseases, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan) ,  Hiyoshi Takumi (Division of Periodontology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan) ,  Domon Hisanori (Division of Microbiology and Infectious Diseases, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan) ,  Domon Hisanori (Research Center for Advanced Oral Science, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan) ,  Maekawa Tomoki (Division of Microbiology and Infectious Diseases, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan) ,  Maekawa Tomoki (Division of Periodontology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan) ,  Maekawa Tomoki (Research Center for Advanced Oral Science, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan) ,  Nagai Kosuke (Division of Microbiology and Infectious Diseases, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan) ,  Tamura Hikaru (Division of Microbiology and Infectious Diseases, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan) ,  Tamura Hikaru (Division of Periodontology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan) ,  Tamura Hikaru (Research Center for Advanced Oral Science, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan) ,  Takahashi Naoki (Division of Periodontology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan) ,  Yonezawa Daisuke (Research Center for Advanced Oral Science, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan) ,  Yonezawa Daisuke (Division of Oral Science for Health Promotion, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan) ,  Miyoshi Tomohiro (Department of Oral Microbiology, Matsumoto Dental University, Shiojiri, Japan) ,  Yoshida Akihiro (Department of Oral Microbiology, Matsumoto Dental University, Shiojiri, Japan) ,  Tabeta Koichi (Division of Periodontology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan) ,  Terao Yutaka (Division of Microbiology and Infectious Diseases, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan) ,  Terao Yutaka (Research Center for Advanced Oral Science, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan)
Material： Microbiology and Immunology  (Microbiol Immunol)
Volume： 63  Issue： 3-4  Page： 100-110  Publication year： Mar. 2019 
JST Material Number： W1957A  ISSN： 0385-5600  Document type： Article
Article type： 原著論文  Country of issue： Australia (AUS)  Language： ENGLISH (EN)

Thesaurus term： *bacterium ,...
Semi thesaurus term： *Aggregatibacter actinomycetemcomitans ,...

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Author keywords (4)： Aggregatibacter actinomycetemcomitans ,  leukotoxin ,  neutrophil elastase ,  periodontitis

JST classification (2)： Physiology and pathogenicity of microbial infection  (EG03053T) ,  Basic dentistry(= odontology)  (GT01020O)

Substance index (2)： ONO-5046 ,  Leukotoxin

Terms in the title (12)： Aggregatibacter ,  ロイコトキシン ,  依存性 ,  好中球 ,  溶解 ,  エラスターゼ ,  放出 ,  ヒト ,  歯肉上皮細胞 ,  線維芽細胞 ,  死 ,  誘導