Art

J-GLOBAL ID：201902261122665269   Reference number：19A2899636

Antidepressant effect of the translocator protein antagonist ONO-2952 on mouse behaviors under chronic social defeat stress

慢性社会的デフェットストレス下のマウス行動に対するtransケータ蛋白質アンタゴニストONO-2952の抗うつ効果【JST・京大機械翻訳】

Author (10)： Nozaki Kanako (Department of Neurobiology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Japan) ,  Ito Hikaru (Department of Neurobiology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Japan) ,  Ohgidani Masahiro (Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Japan) ,  Yamawaki Yosuke (Department of Cellular and Molecular Pharmacology, Graduate of Biomedical and Health Sciences, Hiroshima University, Japan) ,  Sahin Ezgi Hatice (Faculty of Medicine, Hacettepe University, Turkey) ,  Kitajima Takashi (Discovery Research Laboratories, Drug Discovery Division, Discovery & Research ONO Pharmaceutical Co., Ltd, Japan) ,  Katsumata Seishi (Discovery Research Laboratories, Drug Discovery Division, Discovery & Research ONO Pharmaceutical Co., Ltd, Japan) ,  Yamawaki Shigeto (Department of Psychiatry and Neurosciences, Graduate School of Biomedical and Health Sciences, Hiroshima University, Japan) ,  Kato Takahiro A. (Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Japan) ,  Aizawa Hidenori (Department of Neurobiology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Japan)
Material： Neuropharmacology
Volume： 162  Page： Null  Publication year： 2020 
JST Material Number： H0537A  ISSN： 0028-3908  CODEN： NEPHBW  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： In preclinical models, it has ...

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Thesaurus term： animal ,  biomarker ,  inflammation ,  active oxygen ,  lipopolysaccharide ,  microglia ,  cytokine ,  depression(disease) ,  inflammatory cytokine ,  in vitro experiment ,  nucleus accumbens ,  *protein ,  mitochondria ,  *depression(symptom) ,  antidepressive drug

Author keywords (6)： Translocator protein ,  Depression ,  Stress ,  Cytokines ,  Reactive oxygen species ,  Microglia

JST classification (2)： Basic neurology  (GN01020W) ,  Receptors on cell membrane  (EF04030C)

Terms in the title (7)： 慢性 ,  社会 ,  マウス ,  行動 ,  蛋白質 ,  アンタゴニスト ,  うつ