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J-GLOBAL ID：201902262381852683   Reference number：19A1207802

Mice conditionally expressing RET(C618F) mutation display C cell hyperplasia and hyperganglionosis of the enteric nervous system

RET(C618F)突然変異を発現するマウスは腸神経系のC細胞過形成と高神経節症を示す【JST・京大機械翻訳】

Author (9)： Okamoto Mitsumasa (Division for Neural Differentiation and Regeneration, Department of Physiology and Cell Biology, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan) ,  Okamoto Mitsumasa (Department of Pediatric Surgery, Takatsuki General Hospital, Osaka, Japan) ,  Yoshioka Yuta (Division for Neural Differentiation and Regeneration, Department of Physiology and Cell Biology, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan) ,  Yoshioka Yuta (Division of Hepato-Biliary-Pancreatic surgery, Department of Physiology and Cell Biology, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan) ,  Maeda Kosaku (Department of Surgery, Hyogo Prefectural Kobe Children’s Hospital, Kobe, Hyogo, Japan) ,  Bito Yuko (Division of Pediatric Surgery, Department of Surgery, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan) ,  Fukumoto Takumi (Division of Hepato-Biliary-Pancreatic surgery, Department of Physiology and Cell Biology, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan) ,  Uesaka Toshihiro (Division for Neural Differentiation and Regeneration, Department of Physiology and Cell Biology, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan) ,  Enomoto Hideki (Division for Neural Differentiation and Regeneration, Department of Physiology and Cell Biology, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan)
Material： Genesis
Volume： 57  Issue： 5  Page： e23292  Publication year： 2019 
JST Material Number： A1326A  ISSN： 1526-954X  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： Medullary thyroid carcinoma (M...

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Thesaurus term： *Mus musculus ,  allele ,  Heredity ,  *hyperplasia ,  Phenotype ,  Death ,  Thyroid Gland ,  *Mutation ,  promoter (genetics) ,  *Ganglia ,  human ,  cDNA ,  mCherry ,  Ligands ,  *Genetic Variation ,  *Myomorpha ,  aliphatic amine ,  thiol ,  aliphatic carboxylic acid ,  sulfur containing amino acid ,  primary amine
Semi thesaurus term： *variation(biology) , 【Automatic Indexing@JST】

Author keywords (6)： C cell hyperplasia ,  disease model ,  knock-in ,  medullary thyroid carcinoma ,  reporter line ,  ret mutant

JST classification (2)： Cell physiology in general  (EF02010S) ,  Development(=generation)and differentiation  (EJ16020W)

Substance index (1)： Cysteine

Terms in the title (8)： RET ,  突然変異 ,  発現 ,  マウス ,  腸神経系 ,  細胞 ,  過形成 ,  神経節