Art

J-GLOBAL ID：201902263057850967   Reference number：19A1528810

Generation of monocyte-derived tumor-associated macrophages using tumor-conditioned media provides a novel method to study tumor-associated macrophages in vitro

腫瘍条件培地を用いた単球由来腫瘍関連マクロファージの生成はin vitroで腫瘍関連マクロファージを研究する新規方法を提供する【JST・京大機械翻訳】

Author (15)： Benner Brooke (Comprehensive Cancer Center, The Ohio State University, Columbus, USA) ,  Scarberry Luke (Comprehensive Cancer Center, The Ohio State University, Columbus, USA) ,  Suarez-Kelly Lorena P. (Division of Surgical Oncology, The Ohio State University, Columbus, USA) ,  Duggan Megan C. (Comprehensive Cancer Center, The Ohio State University, Columbus, USA) ,  Campbell Amanda R. (Comprehensive Cancer Center, The Ohio State University, Columbus, USA) ,  Smith Emily (Comprehensive Cancer Center, The Ohio State University, Columbus, USA) ,  Lapurga Gabriella (Comprehensive Cancer Center, The Ohio State University, Columbus, USA) ,  Jiang Kallie (Comprehensive Cancer Center, The Ohio State University, Columbus, USA) ,  Butchar Jonathan P. (Comprehensive Cancer Center, The Ohio State University, Columbus, USA) ,  Tridandapani Susheela (Comprehensive Cancer Center, The Ohio State University, Columbus, USA) ,  Howard John Harrison (Division of Surgical Oncology, The Ohio State University, Columbus, USA) ,  Baiocchi Robert A. (Division of Hematology, Department of Medicine, The Ohio State University, Columbus, USA) ,  Mace Thomas A. (Comprehensive Cancer Center, The Ohio State University, Columbus, USA) ,  Carson William E. (Comprehensive Cancer Center, The Ohio State University, Columbus, USA) ,  Carson William E. (Division of Surgical Oncology, The Ohio State University, Columbus, USA)
Material： Journal for ImmunoTherapy of Cancer (Web)
Volume： 7  Issue： 1  Page： 140  Publication year： 2019 
JST Material Number： U7507A  ISSN： 2051-1426  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Abstract/Point： Tumor-associated macrophages (...

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Thesaurus term： *monocyte ,  *tumor ,  *macrophage ,  NK cell ,  lymphoma ,  T cell ,  phenotype ,  solubility(property) ,  human(primates) ,  inactivation ,  arginase ,  tumor cell ,  coculture ,  *in vitro experiment
Semi thesaurus term： 共発現 ,  *腫瘍関連マクロファージ , 【Automatic Indexing@JST】

Author keywords (4)： Tumor-associated macrophages ,  In vitro generation ,  Cancer ,  Immunotherapy

JST classification (3)： Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N) ,  Immunotherapy for tumors  (GE03035B) ,  Immunological reaction in general  (ED03010T)

Reference (55)：

• Front Biosci (Schol Ed); The role of tumor-associated macrophage in tumor progression; K Fukuda, A Kobayashi, K Watabe; 4; 2012; 787-798; citation_id=CR1
• Cell Mol Immunol; The origin and function of tumor-associated macrophages; Y Liu, X Cao; 12; 2015; 1-4; 10.1038/cmi.2014.83; citation_id=CR2
• Nat Immunol; Innate and adaptive immune cells in the tumor microenvironment; TF Gajewski, H Schreiber, Y-X Fu; 14; 2013; 1014-1022; 10.1038/ni.2703; citation_id=CR3
• Cancer Res; Myeloid-derived suppressor cells express Bruton’s tyrosine kinase and can be depleted in tumor-bearing hosts by Ibrutinib treatment; A Stiff, P Trikha, R Wesolowski; 76; 2016; 2125-2136; 10.1158/0008-5472.CAN-15-1490; citation_id=CR4
• Immunity; Tumor-associated macrophages: from mechanisms to therapy; R Noy, JW Pollard; 41; 2014; 49-61; 10.1016/J.IMMUNI.2014.06.010; citation_id=CR5

Terms in the title (5)： 腫瘍 ,  条件培地 ,  単球 ,  腫瘍関連マクロファージ ,  研究